Chemistry of Heterocyclic Compounds: A Series of Monographs

1982

DOI: 10.1002/9780470187036.ch2

|View full text |Cite

|

Sign up to set email alerts

|

Reissert Compounds and Related N ‐Acyldihydroquinolines

¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

0

Mentioning

0

Contrasting

0

Year Published

1983

1983

2010

2010

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 8 publications

References 78 publications

Supporting

0

Mentioning

0

Contrasting

0

Order By: Relevance

Synthesis of bis‐pyrrole tetra esters and alcohols as novel mimetics of the anticancer mitomycin

Iyer²,

et al. 2010

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Open‐chain bis‐Reissert compounds 1 were converted to the corresponding bis‐oxazolium intermediates via acid‐catalyzed intramolecular cyclization. These oxazolium compounds exist in a variety of tautomeric structures in which the meso‐ionic form can be intercepted by reaction with dipolarophiles in a 1,3‐dipolar‐cycloaddition reaction to produce a variety of highly functionalized bis‐pyrrole esters 2. In turn, the bis‐pyrrole esters could be converted to the corresponding bis‐pyrrole tetrols 3 in high yields. J. Heterocyclic Chem., 2011.

Synthesis of bis‐pyrrole tetra esters and alcohols as novel mimetics of the anticancer mitomycin

Iyer²,

et al. 2010

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Open‐chain bis‐Reissert compounds 1 were converted to the corresponding bis‐oxazolium intermediates via acid‐catalyzed intramolecular cyclization. These oxazolium compounds exist in a variety of tautomeric structures in which the meso‐ionic form can be intercepted by reaction with dipolarophiles in a 1,3‐dipolar‐cycloaddition reaction to produce a variety of highly functionalized bis‐pyrrole esters 2. In turn, the bis‐pyrrole esters could be converted to the corresponding bis‐pyrrole tetrols 3 in high yields. J. Heterocyclic Chem., 2011.

Reissert compounds and their open‐chain analogs in organic synthesis

¹

1983

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Reactions of major synthetic interest employing Reissert compounds (1, 2‐dihydro‐1‐acyl‐2‐cyanoquinolines and 1, 2‐dihydro‐2‐aqyl‐1‐cyanoisoquinolines) and related heterocyclic species are surveyed. The chemistry of open‐chain analogs of Reissert compounds (i.e., derivatives of N‐acyl‐α‐aminoacetonitriles) is described and compared with conventional Reissert compounds.

Pyridazines. XXV. Formation of 2‐benzoyl‐2,5‐dihydro‐3‐pyridazinecarbonitrile derivatives in the reissert reaction of pyridazines

¹

,

²

1985

Journal of Heterocyclic Chem

View full text Add to dashboard Cite

Pyridazines 1a, b on treatment with potassium cyanide/benzoyl chloride in a mixed solvent system gave 2‐benzoyl‐2,5‐dihydro‐3‐pyridazinecarbonitriles 3a, b together with products resulting from attack of one mole of cyanide ion and three moles of benzoyl chloride (5a, b). The structures of these novel compounds are proved. A plausible reaction mechanism is proposed, involving rearrangement of initially formed 2a, b into 3a, b. Furthermore, the synthesis of the pyridazine Reissert compound 2a is reported.

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Copyright © 2024 scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.