Reinke’s edema: a proposal for a classification based on morphological characteristics

Vincentiis, Marco de; Ralli, Massimo; Cialente, Fabrizio; Greco, Antonio; Marcotullio, Dario; Minni, Antonio; Kim, Se‐Heon; Remacle, Marc

doi:10.1007/s00405-020-05934-8

Cited by 8 publications

(5 citation statements)

References 25 publications

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“…1 This is a benign laryngeal condition caused by swelling in the lamina propria and can have up to a 3% chance of malignant dysplasia. 1,2 We now report a case of a 56-year-old female cigarette smoker who presented with severe Reinke's Edema and bilateral varices of the vocal cords.…”

Section: Introductionmentioning

confidence: 97%

Acute Variceal Hemorrhage and Airway Obstruction in a Patient With Reinke’s Edema

et al. 2022

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Reinke’s edema and variceal hemorrhage are complex structural pathologies that affect the vocal cord mucosa. The vocal cords are highly susceptible to environmental stressors, such as smoking and vocal cord usage, thus, treatment involves their corresponding cessation.1 Here, we report a case of a patient with severe Reinke’s edema and bilateral chronic vocal cord varices. The patient had a 30-pack-year history of cigarette smoking and was obstructed with intubation due to acute variceal hemorrhage and severe swelling of Reinke’s edema. Moreover, a review of the literature regarding Reinke’s edema and variceal hemorrhage treatment and their complications was performed.

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Section: Introductionmentioning

confidence: 97%

Acute Variceal Hemorrhage and Airway Obstruction in a Patient With Reinke’s Edema

et al. 2022

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“…В таком случае помогает только хирургическое лечение. В ранней стадии положительный эффект дают фонопедия и устранение раздражаю щих факторов [13][14][15].…”

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Chronic edematous-polypous laryngitis (Reinke – Gayek disease) as a cause of hoarseness. Personalized approach to the surgical treatment

et al. 2023

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Introduction. Chronic edematous-polypous laryngitis, Reinke – Gayek’s edema accounts for 5.5% of all benign diseases of the vocal folds. Surgical treatment of Reinke – Gayek disease consists in removing excess mucosa, or “stripping” – tearing off a strip of mucosa with forceps from the vocal fold. The principle of laryngeal surgery is to preserve the structures of the vocal fold, to obtain flexible vibration of the muscular-membranous part and the mucous membrane of the vocal fold.Purpose. Improving the effectiveness of the treatment of patients with Reinke – Hayek edema by developing sparing methods of surgical treatment using a carbon dioxide laser. To develop criteria for choosing a method of sparing surgical treatment of Reinke – Hayek edema using a carbon dioxide laser, depending on the type of edema according to the Yonekawa classification.Materials and methods. 80 patients with Reinke – Gayek’s disease, 59 women and 21 men, from 29 to 77 years old, divided into two subgroups, and a control group were treated. Preoperative examination included endoscopic examination, laryngostroboscopy. The type was determined according to the H. Yonekawa classification. In type II, subgroup 1 – aspiration technique, n = 30. In type III, subgroup 2 – M-shaped technique, n = 30. Control group, it includes patients with type II and III edema, resection technique, n = 20.Results. Patients in the preoperative period were surveyed with the SF-36 Health Status Survey questionnaire, the dysphonia severity index (DSI), as well as the time of maximum phonation. In the postoperative period, they were examined, 1 month after the operation and 6 months after the operation. There is an increase in indicators, an increase in the time of maximum phonation, an increase in SF-36 scores.Conclusion. The use of this technique made it possible to significantly accelerate the recovery of the voice, reduce the time spent in the hospital, minimally damaging the structure of the mucous membrane of the vocal folds.

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“…The first of these staging systems was proposed by Yonekawa in 1988 in which there were three grades 14 . Subsequent systems have stratified these vocal fold changes into four grades but all use endoscopic vocal fold edema and impact on the laryngeal airway to grade severity 15,16 . Patients with more severe exophytic polypoid changes were noted to have more severe impact on vocal fold vibration and thus fail conservative treatment, resulting in more frequent surgical intervention 17–19 .…”

Section: Introductionmentioning

confidence: 99%

“…14 Subsequent systems have stratified these vocal fold changes into four grades but all use endoscopic vocal fold edema and impact on the laryngeal airway to grade severity. 15,16 Patients with more severe exophytic polypoid changes were noted to have more severe impact on vocal fold vibration and thus fail conservative treatment, resulting in more frequent surgical intervention. [17][18][19] This more severe Yonekawa grade II and grade III group was the focus of our evaluation.…”

Section: Introductionmentioning

confidence: 99%

Voice outcomes in high‐grade Reinke's edema: Comparing microflap excision and microdebrider surgery

Bentsianov,

Liang,

Bentsianov

2023

Laryngoscope Investig Oto

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ObjectivesPatients presenting with hoarseness and diagnosed with high‐grade Reinke's edema (RE) will often require surgical intervention for polypoid changes of the true vocal folds. We compared patient outcomes in patients who had microflap or microdebrider excision surgeries.MethodsPatients with the diagnosis of grade II or grade III RE based on laryngoscopy or videostroboscopy who failed conservative management underwent surgery using the standard excision practice of the primary surgeon. Voice outcomes were compared using VHI‐30 (Voice Handicap Index), V‐RQOL (Voice‐Related Quality of Life), and MPT (maximum phonation time) preoperatively and at 1‐month and 6‐months postoperatively.ResultsOf the 115 patients included, there were 46 RE grade II patients and 69 RE grade III patients with 52 patient undergoing microflap surgery and 63 patients undergoing microdebrider surgery. Both procedures resulted in significant improvement in VHI‐30, V‐RQOL, and MPT at 1‐month and 6‐months postoperatively. The microdebrider group had better 6‐month VHI scores (40.84) than the microflap group (44.54) (CI −7.27 to −0.12). The microdebrider group also had better 6‐month V‐RQOL measures (62.56) than the microflap group (57.79) (CI 0.38–9.16).ConclusionBoth microflap excision and microdebrider excision for high‐grade RE lesions resulted in significant improvement in VHI‐30, V‐RQOL, and MPT at 1‐month and 6‐months postoperatively with the microdebrider excision group scoring statistically significantly better at 6 months in comparison to the microflap group. Overall, the results support the use of both surgical modalities for treating high‐grade RE patients.Level of evidence3.

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Reinke’s edema: a proposal for a classification based on morphological characteristics

Cited by 8 publications

References 25 publications

Acute Variceal Hemorrhage and Airway Obstruction in a Patient With Reinke’s Edema

Acute Variceal Hemorrhage and Airway Obstruction in a Patient With Reinke’s Edema

Chronic edematous-polypous laryngitis (Reinke – Gayek disease) as a cause of hoarseness. Personalized approach to the surgical treatment

Voice outcomes in high‐grade Reinke's edema: Comparing microflap excision and microdebrider surgery

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