Reinitiation of Gonadotropin Release in Underfed Rats by Constant Light or Epinephrine¹

Modification of the Oestrous Cycle of the Underfed Rat Associated With the Time of Feeding

“…Oestrous activity may be resumed in a group of such non-cycling rats when they are subjected to the stimulus of constant illumination (Piacsek & Meites, 1965) and the long irregular cycles of underfed rats become more normal in the presence of the male (Cooper & Haynes, 1967). In the underfed gilt, a period of re-feeding just before ovulation appears to increase the ovulation rate (Lodge & Hardy, 1968) and, conversely, starvation of mice just before oestrus prevents ovulation (McClure, 1967).…”

Effect of Dietary Restriction on Ovarian Compensatory Hypertrophy in the Rat

“…This is generally attributed to an impaired secretion of pituitary gonadotrophins (Piacsek & Meites, 1967;Howland, 1971a; Negro-Vilar, Dickerman & Meites, 1971). Recently, Howland (1971bHowland ( , c, 1972 has examined the ability of the underfed rat to exhibit the compensatory ovarian hypertrophy following unilateral ovariectomy that is known to occur in the fully fed animal (Benson, Sorrentino & Evans, 1969).…”

Ovarian Weight and Ovarian Compensatory Hypertrophy in the Rat as Affected by Duration of Underfeeding

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The detrimental effects of underfeeding on ovarian function in the female rat are characterized by cessation of oestrous cycles and ovarian atrophy (Rinaldini 1949;Piacsek & Meites, 1967

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“…The detrimental effects of underfeeding on ovarian function in the female rat are characterized by cessation of oestrous cycles and ovarian atrophy (Rinaldini 1949;Piacsek & Meites, 1967). These effects appear to be the result of impaired release of gonadotrophins due to deficient secretion of hypothalamic gonadotrophin releasing factors (Piacsek & Meites, 1967).…”

“…These effects appear to be the result of impaired release of gonadotrophins due to deficient secretion of hypothalamic gonadotrophin releasing factors (Piacsek & Meites, 1967). Decreased basal levels of plasma lh have been demonstrated in female rats after 20 days of restricted feed intake (Howland & Ibrahim, 1971).…”