Reimplantation of a Human Embryo With Subsequent Tubal Pregnancy

Steptoe, P. C.; Edwards, R. G.

doi:10.1016/s0140-6736(76)92096-1

Cited by 319 publications

(82 citation statements)

References 6 publications

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“…It is well-known that the first pregnancy by IVF-ET was ectopic (1). Ovarian pregnancy following IVF-ET was first demonstrated by Marcus and Brinsden (2) but is still rare despite the increased incidence of ectopic pregnancies, accounting for 2 to 11% after IVF-ET (3)(4)(5)(6)(7)(8)(9)(10)(11)(12).…”

Section: Discussionmentioning

confidence: 99%

A case of primary ovarian pregnancy after in vitro fertilization and embryo transfer

Shibahara

Funabiki

Shiotani

et al. 1997

J Assist Reprod Genet

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Section: Discussionmentioning

confidence: 99%

A case of primary ovarian pregnancy after in vitro fertilization and embryo transfer

Shibahara

Funabiki

Shiotani

et al. 1997

J Assist Reprod Genet

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“…In the 1960s and 1970s, it was reported that in vitro matured oocytes could be fertilized in vitro in many mammals including humans (Edwards et al 1969), mice (Cross & Brinster 1970, Iwamatsu & Chang 1972, Mukherjee 1972, rabbits (Brackett et al 1972), guinea pigs (Yanagimachi 1974), hamsters (Whittingham & Bavister 1974), rats (Niwa & Chang 1975, Niwa et al 1976, cows (Iritani & Niwa 1977), and pigs (Iritani et al 1978). Moreover, live young were obtained from in vitro matured oocytes in mice (Mukherjee 1972), rabbits (Mills et al 1973), humans (Steptoe & Edwards 1976), cows (Hanada 1985), and pigs (Mattioli et al 1989). From the studies on in vitro fertilization (IVF) and in vitro maturation of mammalian oocytes, it has been recognized that nuclear maturation of oocytes does not guarantee their ability to be fertilized and to develop to term and that the maturation of the cytoplasm is essential (Eppig 1996).…”

Section: Introductionmentioning

confidence: 99%

Development of a reliable in vitro maturation system for zebrafish oocytes

Seki¹,

Kouya²,

Tsuchiya³

et al. 2008

Reproduction

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In zebrafish oocytes, it has been reported that a 60 or 75% Leibovitz L-15 medium or simple balanced saline solution containing 17a, 20b-dihydroxy-4-pregnen-3-one (DHP) is effective for nuclear maturation. However, most of the oocytes that matured under these conditions were not fertilized and did not hatch. Thus, these in vitro maturation methods could not support the cytoplasmic maturation of zebrafish oocytes. Therefore, we tried to develop a reliable in vitro maturation method for zebrafish oocytes, which supports their ability to be fertilized and to develop till hatching. When zebrafish oocytes at stage III were cultured in 50-100% Leibovitz L-15 medium supplemented with DHP, the highest rates of cleavage (24%) and hatching (12%) were obtained from oocytes matured in 90% Leibovitz L-15 medium. When we examined the suitable pH (7.5-9.5) of the 90% medium, higher rates of cleavage (45%) and hatching (33%) were obtained in oocytes matured at pH 9.0 than at pH 7.5, 8.5, or 9.5 (cleavage rate, 16-29%; hatching rate, 8-21%). In oocytes matured in 90% Leibovitz L-15 medium at pH 9.0, high rates of cleavage (70%) and hatching (63%) were obtained when oocytes were cultured for 270 min with 0.5 mg/ml BSA. Thus, 90% Leibovitz L-15 medium at pH 9.0 containing 0.5 mg/ml BSA was effective for normal maturation of zebrafish oocytes. This method will become a powerful tool for understanding the mechanism of in vitro maturation in zebrafish oocytes and for the practical use of immature oocytes.

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“…was ectopic, in a patient with history of tubal factor infertility [5]. Theories regarding the genesis of spontaneous ectopic pregnancy are well known.…”

Section: Discussionmentioning

confidence: 99%

Bilateral ectopic tubal pregnancy, following in vitro fertilisation (IVF).

Issat

Grzybowski²,

Jakimiuk³

2010

Folia Histochem Cytobiol.

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This is a case report of a 33 year-old-woman who underwent in vitro fertilization, because of primary infertility caused by fallopian tube factor. The patient underwent three trials of frozen embryo transfers (ET-CRYO). On the 26 th day after the third probe of ET-CRYO she suffered from pelvic pain and vaginal bleeding. Transvaginal ultrasonographic scan revealed bilateral tubal ectopic pregnancy without fluid in the Douglas pouch and no gestational sac in the uterus. Laparoscopic bilateral salpingectomy was performed on the next day after admission. The postoperative course was uneventful.

show abstract

Reimplantation of a Human Embryo With Subsequent Tubal Pregnancy

Cited by 319 publications

References 6 publications

A case of primary ovarian pregnancy after in vitro fertilization and embryo transfer

A case of primary ovarian pregnancy after in vitro fertilization and embryo transfer

Development of a reliable in vitro maturation system for zebrafish oocytes

Bilateral ectopic tubal pregnancy, following in vitro fertilisation (IVF).

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