Rehospitalization needs in a cardiac transplantation unit

Cristóbal, Carmen; Pulpón, L. Alonso; Núñez, Ángela; Segovia, Javier; Page, Juan C. Gallego

doi:10.1016/s0041-1345(99)00497-2

Cited by 5 publications

(7 citation statements)

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“…reported 37% rehospitalization over 4 years among adult Htx recipients who survived at least 6 months post‐transplant, and Donovan et al. reported rehospitalization in 36% of adult patients in the first post‐transplant year . Both studies found that the most common indication for rehospitalization was infection (40% in both studies), with rejection being relatively rare at 12% and 14%, respectively .…”

Section: Discussionmentioning

confidence: 97%

“…reported rehospitalization in 36% of adult patients in the first post‐transplant year . Both studies found that the most common indication for rehospitalization was infection (40% in both studies), with rejection being relatively rare at 12% and 14%, respectively . Neither of those studies, however, analyzed hospitalization patterns in detail, and thus, a comparison of rehospitalization characteristics or outcomes for specific subgroups could not be made.…”

Section: Discussionmentioning

confidence: 99%

“…Rehospitalization has been well studied in adult solid organ transplant recipients, but less is known about this phenomenon in the pediatric Htx population . In 2010, Tsao et al.…”

Section: Introductionmentioning

confidence: 99%

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Rehospitalization after pediatric heart transplantation: Incidence, indications, and outcomes

Hollander

McElhinney²,

Almond

et al. 2016

Pediatric Transplantation

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We report the patterns of rehospitalization after pediatric heart transplant (Htx) at a single center. Retrospective review of 107 consecutive pediatric Htx recipients between January 22, 2007, and August 28, 2014, who survived their initial transplant hospitalization. The frequency, duration, and indications for all hospitalizations between transplant hospitalization discharge and September 30, 2015, were analyzed. A total of 444 hospitalization episodes occurred in 90 of 107 (84%) patients. The median time to first rehospitalization was 59.5 (range 1-1526) days, and the median length of stay was 2.5 (range 0-81) days. There were an average of two hospitalizations per patient in the first year following transplant hospitalization, declining to about 0.8 per patient per year starting at 3 years post-transplant. Admissions for viral infections were most common, occurring in 93 of 386 (24%), followed by rule out sepsis in 61 of 386 (16%). Admissions for suspected or confirmed rejection were less frequent, accounting for 41 of 386 (11%) and 31 of 386 (8%) of all admissions, respectively. Survival to discharge after rehospitalization was 97%. Hospitalization is common after pediatric Htx, particularly in the first post-transplant year, with the most frequent indications for hospitalization being viral illness and rule out sepsis. After the first post-transplant year, the risk for readmission falls significantly but remains constant for several years.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Rehospitalization after pediatric heart transplantation: Incidence, indications, and outcomes

Hollander

McElhinney²,

Almond

et al. 2016

Pediatric Transplantation

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show abstract

“…Despite its efficacy, the side effects of cyclosporine are especially pronounced; beyond producing disturbances in patients’ physiological, psychological and social wellbeing, cyclosporine may be a significant threat to the health and safety of transplant patients. Post‐transplantation complications commonly seen in the literature include rejection, infection, renal failure, hyperlipidaemia, hypertension, diabetes, osteoporosis, malignant tumours (Wagoner 1997, Cristobal et al. 1999, Augustine 2000, Donovan et al.…”

Section: Introductionmentioning

confidence: 99%

“…In general, there is significant morbidity in the first year after transplantation and the number of readmissions is also high. Cristobal et al. (1999) examined data from 212 patients who survived for at least six months after heart transplantation between 1984 and 1996.…”

Section: Introductionmentioning

confidence: 99%