Rehabilitation provided to patients with rheumatoid arthritis: A comparison of three different rheumatology clinics in Austria, Sweden and the UK from the perspectives of patients and health professionals

Prodinger, Birgit; Ndosi, Mwidimi; Nordenskiöld, Ulla; Stamm, Tanja; Persson, Gert; Andreasson, Ingrid; Lundgren‐Nilsson, Åsa

doi:10.2340/16501977-1914

Cited by 7 publications

(2 citation statements)

References 31 publications

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“…In recent decades, many countries around the world have been developing the system of medical rehabilitation aimed at restoration of functional ability and quality of life to those with physical impairments, as well as their maximal integration or reintegration in society and prevention of disability [8][9][10][11][12]. It should be noted that each country arranges the system of medical rehabilitation according to its national requirements.…”

Section: Review and Discussionmentioning

confidence: 99%

Medical Rehabilitation System and Its Quality Control in Developed Countries of the World

et al. 2020

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The aim: To review scientific literature dealing with evaluation of medical rehabilitation effectiveness and quality in the world. Materials and methods: Review and generalization of scientific literature on the criteria of evaluation of medical rehabilitation quality in advanced industrialized societies. Conclusions: Despite differences in the structure of medical rehabilitation in world societies, the end point is similar – assessment of quality of life of a sick person, measured by various criteria and standards. This experience is of great value for the development of national system of rehabilitation services.

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Section: Review and Discussionmentioning

confidence: 99%

Medical Rehabilitation System and Its Quality Control in Developed Countries of the World

et al. 2020

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“…It is reported that heritability of RA was ranging from 15 to 60%, indicating genetic factor as one of the pathogenic factors [2]. In addition, a variety of environmental factors, immune cells and cytokines, such as smoking, T cells, B cells, TLRs (Toll-like receptor) and virus are involved in the pathological process [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Network analysis indicating the pharmacological mechanism of Yunpi-Qufeng-Chushi-prescription in prophylactic treatment of rheumatoid arthritis

Zhou

Liu

et al. 2021

BMC Complement Med Ther

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Background Rheumatoid arthritis (RA), is an autoimmune inflammatory disease with increasing global morbidity and high disability. Early treatment is an effective intervention to slow down joint deformation. However, as for early RA and pre-RA patients, it sometimes takes a long time to make a definite diagnosis and few guidelines have made suggestion for these suspected or early phrase individuals. Yunpi-Qufeng-Chushi-Prescription (YQCP) is an optimization of the traditional formula, Cangzhu Fangfeng Tang which is effective for arthromyodynia management. Methods In this study, LC-MS identify the main component of YQCP. Ingredients of the 11 herbs were collected from Traditional Chinese Medicine Integrated Database (TCMID). Targets of these ingredients were collected from two source, TCMID and PharmMapper. Microarray of 20 early untreated RA patients and corresponding health control were download from NCBI Gene Expression Omnibus (GEO) database to defined the differential expressed genes. Gene ontology analysis and KEGG enrichment analysis were carried out for the YQCP. Protein-protein interactions (PPIs) networks were constructed to identify the hub targets. At last, molecular docking (MD) were conducted to further verified the the possibility of YQCP for RA therapy. Result The study indicated that by acting on hub targets such as C3, EGFR, SRC and MMP9, YQCP may influence the mature of B cells and inhibit B cell-related IgG production, regulate oxidative stress and modulate activity of several enzymes including peroxidase and metallopeptidase to delay the occurrence and progress of RA and benefit the pre-RA or early RA patients. Conclusion YQCP is a potential effective therapy for prophylactic treatment of RA.

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Variability in the prescription of biological drugs in rheumatoid arthritis in Spain: a multilevel analysis

et al. 2018

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To describe variability in the prescription of biologics (B-DMARDs) for patients with rheumatoid arthritis (RA) in hospitals in Spain, and to explore which characteristics of the patient, the doctor and the hospital are associated with this variability. Cross-sectional multicentric study in 46 rheumatology services of the National Health System. Medical records of 1188 randomly selected patients were reviewed. The association of each variable with B-DMARD prescription was analyzed using simple logistic regressions. Multilevel logistic regression models were created to analyze variability among centers. 36.8% of patients had received B-DMARD. The proportion of patients being treated with B-DMARDs varied between 3.6 and 71.4% depending on the center. Association of prescription of B-DMARD with patient age (OR = 0.958, 95% CI = 0.947-0.968, p < 0.001), longer disease duration (OR = 1.05, 95% CI = 1.032-1.069, p < 0.001), higher CRP levels (OR = 1.022, 95% CI = 1.003-1.042, p = 0.023), and higher number of hospitalizations (OR = 1.286, 95% CI = 1.145-1.446, p < 0.001) was observed. With regard to the center characteristics, the existence of telephone consultations (OR = 1.438, 95% CI = 1.037-1.994, p = 0.03) and the number of beds (OR = 1.045, 95% CI = 1.001-1.091, p = 0.044) were positively associated with prescription of B-DMARDs. Patient variables explained 34.04% of the variability among centers. By adjusting for patient and hospital characteristics, it went up to 83.71%. There is variability in the prescription of B-DMARDs for patients with RA among hospitals which is associated, to a greater extent, with the center characteristics. B-DMARDs prescription could be partly explained by other factors not covered by the current study including the provider's attitudes towards biologics and other hospital characteristics.

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Rehabilitation provided to patients with rheumatoid arthritis: A comparison of three different rheumatology clinics in Austria, Sweden and the UK from the perspectives of patients and health professionals

Abstract: Integration of patients' and health professionals' views on how rehabilitation services are coordinated and how (parts of) processes are set up elsewhere provide valuable information for the further optimization of rehabilitation services.

Cited by 7 publications

References 31 publications

Medical Rehabilitation System and Its Quality Control in Developed Countries of the World

Medical Rehabilitation System and Its Quality Control in Developed Countries of the World

Network analysis indicating the pharmacological mechanism of Yunpi-Qufeng-Chushi-prescription in prophylactic treatment of rheumatoid arthritis

Variability in the prescription of biological drugs in rheumatoid arthritis in Spain: a multilevel analysis

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