Rehabilitation of peripheral facial palsy associated with COVID-19 in a child: A case report

Ferreira, Eduardo Freitas; Portugal, Diogo; Silva, Nuno; Peixoto, Catarina; Matos, Catarina; Prates, Leonor

doi:10.1016/j.rehab.2021.101600

Cited by 8 publications

(15 citation statements)

References 19 publications

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“…Studies based on the neurological manifestations of COVID-19 in the literature show that the frequency reaches 36% in adults, while a limited number of pediatric reports show variations between 4–28%, similar to our study. [6–26] Similar to the literature, major neurological manifestations among our patients were headache (n:17, 7%), anosmia/hyposmia (n:17, 7%) and seizure (n:4, 1.6%). However, unlike some studies, headache and hyposmia/anosmia were found with equal frequency in our study.…”

Section: Discussionsupporting

confidence: 85%

“…Unlike the literature, in our study, the number of boys (n:13, 37.1%) was slightly smaller than the number of girls (n:22, 62.9%) in Group 1. [6–26] Most studies have reported that there is no gender difference in terms of neurological findings among children. [6–26] However, 1 study reported that headache was more common in girls.…”

Section: Discussionmentioning

confidence: 99%

“…Although data on the age of COVID-19-infected children with neurological findings are limited, reports show that these findings are more common in young children. [6–26] The literature also shows the occurrence of seizures in older children. [24,26,56,57] However, a study reported that the frequency of seizures increased in young children, occurring at a rate of 38% under the age of 5 years.…”

Section: Discussionmentioning

confidence: 99%

“…[6–26] Most studies have reported that there is no gender difference in terms of neurological findings among children. [6–26] However, 1 study reported that headache was more common in girls. [9] Interestingly, in our study, no statistically significant difference was found between children with and without headache in terms of gender.…”

Section: Discussionmentioning

confidence: 99%

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Neurological symptoms and signs associated with COVID-19 in pediatric patients: a single-center experience

Okur¹

2022

Medicine

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There is insufficient evidence on SARS-CoV-2 induced neurological effects. Studies on CNS involvement during COVID-19 in children are limited. This study aims to identify and manage the neurological signs and symptoms in COVID-19-infected pediatric patients during follow up and plan future follow-ups.Children diagnosed COVID-19 and hospitalized in the pediatric pandemic services, between March 18, 2020, and June 18, 2021, were included in the study. Children with underlying neurological disease were excluded from the study. Patient data retrieved from hospital files and medical records. Children divided into 2 groups, 1 and 2, based on the presence or absence of neurological findings.A total of 243 children received follow-ups in the pandemic wards, 35 (14.4%) of these patients had neurological findings. Major neurological manifestations were headache (n:17, 7%), seizure (n:4, 1.6%), and anosmia/hyposmia (n:17, 7%). The number of boys (n:13, 37.1%) was smaller than the number of girls (n:22, 62.9%) in Group 1. Group 1 showed higher blood leukocyte, lymphocyte, thrombocyte, AST, LDH, d-dimer values. Anosmia/hyposmia occurred more often in girls, anosmia and headache occurred more often over 9 years of age. Pulmonary and hematologic involvement was more common in children with anosmia and headache.Our study is one of the few studies on neurological involvement in COVID-19 in children. To the best of our knowledge, there is limited data on these subjects in the literature. Abbrevations: AST = aspartate aminotransferase, CK = creatine kinase, CNS = central nervous system, COVID-19 = new type of coronavirus disease, CRP = C-reactive protein, CT = computed tomography, LDH = lactate dehydrogenase, NIMV = noninvasive mechanical ventilation, PICU = pediatric intensive care unit, PCR = polymerase chain reaction, SPSS = Statistical Package for the Social Sciences, WHO = world health organization.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Neurological symptoms and signs associated with COVID-19 in pediatric patients: a single-center experience

Okur¹

2022

Medicine

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“…In total, our search strategy revealed 215 articles (Figure 1, Table 2). After excluding duplicates and those not meeting inclusion criteria, a total of 32 papers were included in the current review with 46 patients, with an equal number ( n = 23) of males and females [11–42]. The maximum number of cases were from Brazil ( n = 9) and Turkey ( n = 9), followed by the United States ( n = 8), Iran ( n = 4), and Spain ( n = 3).…”

Section: Resultsmentioning

confidence: 99%

Surge of Bell's Palsy in the era of COVID‐19: Systematic review

Gupta

Jawanda²

2022

Euro J of Neurology

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Background and purpose With the progression of coronavirus infectious disease 2019 (COVID‐19), various neurological manifestations have been noticed in infected patients, and Bell's Palsy (BP) is one of the peripheral neuropathies among those. BP has been associated with various other viral agents. Its evidence in patients with COVID‐19 signifies the possibility of association between BP and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). This research was undertaken to evaluate the number of published cases of BP as the only major neurological manifestation in patients with COVID‐19 from March 2020 to December 2021 and to investigate the association of SARS‐CoV‐2 and BP. Methods A systematic review of the published English literature was performed using an electronic search in the PubMed/Medline, Scopus, Research Gate, Research Square, and Google Scholar databases, using keywords such as "COVID‐19" OR/AND "SARS‐CoV‐2" OR/AND "Bell's palsy" OR/AND "facial nerve palsy" OR/AND "neurological" OR/AND "manifestation". Results The search strategy revealed 32 relevant publications with a total of 46 patients. BP was the initial manifestation in 37% of cases, and in 63% of cases it developed after COVID‐19 symptoms; 71.7% of cases showed complete recovery, and 21.7% showed only partial relief from BP. Conclusions Although the number of documented cases in this research is low, evidence of BP as the only major neurological manifestation in patients with COVID‐19 signifies an important clinical finding and the possibility of another viral etiology of BP. More evidence is needed to establish the exact correlation between these two entities.

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A review of the potential neurological adverse events of COVID-19 vaccines

et al. 2022

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Despite the advantages of getting access to the coronavirus disease 2019 (COVID-19) vaccines, their potential ability to induce severe adverse events (AEs) has been a significant concern. Neurological complications are significant among the various adverse events following immunization (AEFI) due to their likely durability and debilitating sequelae. Neurological AEs following COVID-19 vaccination can either exacerbate or induce new-onset neuro-immunologic diseases, such as myasthenia gravis (MG) and Guillain–Barre syndrome (GBS). The more severe spectrum of AEs post-COVID19 vaccines has included seizures, reactivation of the varicella-zoster virus, strokes, GBS, Bell’s palsy, transverse myelitis (TM), and acute disseminated encephalomyelitis (ADEM). Here, we discuss each of these neurological adverse effects separately.

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Rehabilitation of peripheral facial palsy associated with COVID-19 in a child: A case report

Cited by 8 publications

References 19 publications

Neurological symptoms and signs associated with COVID-19 in pediatric patients: a single-center experience

Neurological symptoms and signs associated with COVID-19 in pediatric patients: a single-center experience

Surge of Bell's Palsy in the era of COVID‐19: Systematic review

A review of the potential neurological adverse events of COVID-19 vaccines

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