Rehabilitation Needs in Cancer Treatment-Related Cardiotoxicity

Pituskin, Edith; Kirkham, Amy A.; Cox-Kennett, Nanette; Dimitry, Rebecca; Dimitry, John; Paterson, Ian; Gyenes, Gábor

doi:10.1016/j.soncn.2020.150986

Cited by 4 publications

(5 citation statements)

References 37 publications

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“…Moreover, those patients that had comorbid conditions, such as CVD, had similar or worse survival compared to survivors with a higher stage of breast cancer without these comorbid conditions [ 36 ]. Early recognition of patients who are at risk of cardiac toxicity from their treatment and other risk factors for cardiac disease is essential in improving outcomes for breast cancer survivors [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

A Cardiac Rehabilitation Program for Breast Cancer Survivors: A Feasibility Study

Zvinovski

Ramaswamy

Reinbolt

et al. 2021

Journal of Oncology

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Purpose. The purpose of this study was to determine the feasibility and preliminary efficacy of a cardiac rehabilitation (CR) intervention in the breast cancer population. Methods. This single-arm feasibility study evaluated a 14-week CR intervention program in breast cancer survivors. Feasibility was defined as completion of at least 30/36 sessions of the program without serious adverse events (SAE) in 80% of patients. Secondary endpoints included the change in VO2 max, cardiovascular disease (CVD) risk factors, Duke Activity Secondary Index (DASI), Brief Fatigue Inventory (BFI), and QLQ-C30. All outcomes were reported as mean change and compared using paired t-tests. Results. A total of 25 patients were enrolled in the study. 18 patients of the 25 enrolled (72%) completed the 14 weeks program without SAE. The overall adherence to the study protocol was 60%. Of the 18 participants who did not withdraw from the program, 15 (83%) adhered to the study protocol and completed 30 or more sessions. There was a nonsignificant improvement in VO2 max (mean Δ0.5, p = 0.6 ). The scores for DASI, BFI, and QLQ-C30 improved from baseline to posttreatment. Conclusion. A CR intervention in breast cancer survivors had high adherence in those who were able to complete the 14-week program. The program significantly improved patient reported physical activity, fatigue, and quality of life (QoL), without significant improvement in CVD risk factors. Implications for cancer patients are that early implementation of a CR program should be considered by practitioners as it improves QoL and exercise tolerance in breast cancer survivors.

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Section: Discussionmentioning

confidence: 99%

A Cardiac Rehabilitation Program for Breast Cancer Survivors: A Feasibility Study

Zvinovski

Ramaswamy

Reinbolt

et al. 2021

Journal of Oncology

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“…Additionally, the cardiac nurse supports risk factor and lifestyle modification such as exercise, obesity, tobacco, illicit drug and alcohol use and support for hypertension and diabetes. This cardiac nurse's role has many opportunities for further development such as developing interdisciplinary skills with Oncology Nurse Colleagues, in training and education, in personalizing heart failure care for patients with cancer using risk factor assessments and developing emotional burden risk score for patient with dual cancer and cardiac diseases in effort to improve HR-QoL [10,15].…”

Section: Cardio-oncology Clinic/unitmentioning

confidence: 99%

“…Nurse-led support is offered in the cardiology setting, with regard to patient selfmanagement of their chronic condition, as well as within the oncology setting [9]. Figure 1 illustrates the management of care of a person with cancer and CVD, where the nurse plays a key role as the coordinator of the inter-disciplinary team, and/or using his/her advanced knowledge, skills as an autonomous practitioner, to contribute as clinical expert, researcher, educator, and consultant in health policies [10].…”

Section: Introductionmentioning

confidence: 99%

Personalizing Heart Failure Care to the Patient With Cancer

Lambrinou

DeCourcey

Hill³

2022

Curr Heart Fail Rep

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Purpose of ReviewThe current review describes the role of the cardio-oncology nurse and the need for personalized heart failure care for the patient with cancer. Recent Findings It is a new role whereby cardiology or heart failure nurses care for patients with cancer who develop cardiotoxicity or cardiovascular diseases, either during the cancer therapy or in a later stage. Inter-disciplinary approach is important for individualized early treatment, shortened interruptions to cancer therapy, and irreversible cardiovascular injury prevention. Nurses have a key role in early evaluation and quality control of the care provided. Summary This is a quite new clinical area and not much evidence exists for the development of clinical guidelines and pathways to support clinicians. More trials are needed for the development of clinical recommendations.

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“…Aunque existe una variación individual para el desarrollo de toxicidad, el riesgo de desarrollar miocardiopatía aumenta exponencialmente con dosis acumuladas mayores de 400 mg/m 2 , con una incidencia promedio de 5,1 % con 400 mg/m 2 y de 15,7 % a 500 mg/m 5,27 .…”

Section: Revisemos Estos Agentes Cardiotóxicosunclassified

“…El tratamiento para el cáncer se individualiza en función de factores diagnósticos, pronósticos e individuales, siendo multidimensional e incluyendo cirugía, radioterapia, quimioterapia, terapia dirigida (agentes biológicos) y terapia hormonal; si bien todas estas intervenciones son efectivas de forma aislada o combinada, los sobrevivientes tienen un mayor riesgo de muerte por enfermedad cardiovascular (ECV) que por cáncer 5 . Quienes viven al menos cinco años después del diagnóstico tienen un riesgo de 1,3 a 3,6 veces mayor de mortalidad por ECV, además de una incidencia de 1,7 a 18,5 veces mayor de factores de riesgo ECV como hipertensión, diabetes mellitus y dislipidemia, en comparación con homólogos de la misma edad sin antecedentes de cáncer 6 .…”

Section: Introductionunclassified

Rehabilitación oncológica en cardiotoxicidad: rompiendo paradigmas en la atención al sobreviviente de cáncer

Rojas

Mojica

Capacho

et al. 2021

Rev Col Med Fis Rehab

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Con avances progresivos en la detección y el tratamiento del cáncer, la supervivencia ha mejorado drásticamente en las últimas décadas. El cáncer y las enfermedades cardiovasculares son las principales causas de muerte en los países de ingresos altos. Se pueden encontrar complicaciones cardiovasculares en pacientes con cáncer como resultado de la denominada ‘cardiototoxicidad’. Existe una serie de tratamientos contra el cáncer que se han asociado con diversos grados de lesión cardiovascular, los cuales pueden mostrar consecuencias cardiovasculares hasta años después de la finalización del tratamiento del cáncer. El desarrollo de disfunción cardíaca relacionada con el tratamiento del cáncer tiene un alto riesgo de morbilidad y mortalidad. La detección temprana de los factores de riesgo parece fundamental para prevenir enfermedades cardiovasculares a largo plazo. En esta revisión se analizaron los factores de riesgo de la terapia sistémica y la radioterapia como generadores de cardiototoxicidad.

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Rehabilitation Needs in Cancer Treatment-Related Cardiotoxicity

Cited by 4 publications

References 37 publications

A Cardiac Rehabilitation Program for Breast Cancer Survivors: A Feasibility Study

A Cardiac Rehabilitation Program for Breast Cancer Survivors: A Feasibility Study

Personalizing Heart Failure Care to the Patient With Cancer

Rehabilitación oncológica en cardiotoxicidad: rompiendo paradigmas en la atención al sobreviviente de cáncer

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