“…Following TKA, anxiety may predispose patients to avoid stimuli, activities, sensations or situations that they fear will exacerbate their condition ( Theunissen et al, 2012 ), such as musculoskeletal physiotherapy rehabilitation programs that may cause pain or re-injury ( Jack et al, 2010 ). This can result in longer-term adverse outcomes such as physical deconditioning, comorbidities, loss of function and muscle tone, and enduring chronic pain ( Bortz, 1984 ; Sullivan et al, 2009 ; Powell et al, 2013 ). Avoidance behaviors, therefore, can ultimately lead to augmentation of the outcome that an individual is seeking to diminish ( DeGaetano et al, 2016 ), such as worse pain intensity and longer-term disability ( Goubert and Trompetter, 2017 ), resulting in further avoidance and the perpetuation of a detrimental fear-avoidance behavioral cycle ( Theunissen et al, 2012 ).…”