Abstract:Evolutionary innovation of transcription factors frequently drives phenotypic diversification and adaptation to environmental change. Rewiring, that is gaining or losing connections to transcriptional target genes, is a key mechanism by which transcription factors evolve and innovate. However the frequency of functional adaptation varies between different regulators, even when they are closely related. To identify factors influencing propensity for rewiring, we utilise a Pseudomonas fluorescens SBW25 strain re… Show more
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