Regulatory Mechanisms in House-Mouse Populations: The Effect of Limited Food Supply on an Unconfined Population

Strecker, Robert L.

doi:10.2307/1931124

Cited by 51 publications

(14 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Four factors may have contributed to the low rates of dispersal from coops in this study: the presence of abundant food (Strecker, 1954); shelter (Newsome, 1969b); low population density; and a long period between when the introduced females were captured and when they were released (Ramsey and Briese, 1971). The introduced females probably gained two advantages by being introduced in January.…”

Section: Discussionmentioning

confidence: 93%

Gene Flow in House Mice: Introduction of a New Allele Into Free‐living Populations

Baker

1981

Evolution

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 93%

Gene Flow in House Mice: Introduction of a New Allele Into Free‐living Populations

Baker

1981

Evolution

View full text Add to dashboard Cite

“…-Resources of commensal populations fluctuate in availability, which causes fluctuation in population size (Strecker 1954;Gallagher 1969;Stickel 1979;Baker 1981;Petras and Topping 1981). Deme carrying capacity.…”

Section: Random Mating (Dominance Polygyny)-mentioning

confidence: 99%

The Role of Deme Size, Reproductive Patterns, and Dispersal in the Dynamics of t-Lethal Haplotypes

Nunney¹,

Baker²

1993

Evolution

View full text Add to dashboard Cite

The t-lethal haplotypes (t) found in house mouse (Mus musculus) populations are recessive lethals favored by gametic selection whereby male heterozygotes exhibit a non-Mendelian transmission ratio of about 95% t. The expected equilibrium frequency is 0.385; however, empirical values are lower, averaging close to 0.13. We examined the hypothesis that interdemic selection is the cause of the low empirical values by using a deme-structured simulation model that included overlapping generations, a realistic breeding system, differential deme productivity, and a large total population. We found that under some conditions interdemic selection could lower t frequency below 0.13 in the face of immigration rates up to 5%. Low frequencies were correlated with effective deme size (n ), regardless of whether n was changed through changing deme size (n) or through changing the proportion of breeding adults. Earlier workers showed how the first two phases of interdemic selection (random genetic differentiation and mass selection) interacted to reduce the haplotype frequency, but here we show the importance of the third phase (differential productivity of demes) once demes are linked by dispersal. The effect of this phase is not due to the (negative) covariation between deme productivity and haplotype frequency, but occurs when differential deme productivity generates a difference in t frequency between the population of juveniles recruited into their natal deme and the population of juvenile dispersers. This difference was maximized when the average productivity of demes was low, either because few adult females bred at any one time and/or because fecundity was low. Contrary to an earlier prediction, male-biased dispersal also reduced haplotype frequency, and this probably stems from the relative excess of wild-type genotypes among dispersers compared to the deme residents. Another unexpected finding was that the randomly generated excess of heterozygotes (F < 0) found in small demes favored t haplotypes; however, the effect was only seen when the more powerful influence of the third phase of interdemic selection was removed. Simulations of neutral polymorphisms showed that a deme structure giving F ≤ 0.6 is inconsistent with a haplotype frequency below 0.13. Based on current empirical estimates of F (about 0.2), we concluded that immigration rates in the field are too high for interdemic selection alone to cause the observed deficit of lethal haplotypes. One factor that could combine with population structure effects is the observation that the transmission ratio is lowered to around 0.6 in litters produced from postpartum estrus (PPE). Incorporating this factor, we showed that interdemic selection could be effective in lowering the frequency of t below 0.13 when F was above 0.43 even when migration rates were up to 10%. These results suggest that if empirical haplotype and F estimates are accurate, then additional factors such as a lowered fitness of heterozygotes may be involved.

show abstract

“…Strecker & E m 1 e n (1953) recorded that the discontinuance of population growth in confined populations was due to a cessation of reproduction. On the other hand no decline in the reproduction rate was observed in unconfined populations (Strecker, 1954) as there was a possibility of migration. Crowcroft & Rowe (1957) considered a decline in the reproduction of females as the main factor reducing the increase of a confined population.…”

Section: Discussionmentioning

confidence: 85%

The effect of exploitation on the productivity of laboratory mouse populations

Walkowa¹

1971

Acta Theriol.

View full text Add to dashboard Cite

Regulatory Mechanisms in House-Mouse Populations: The Effect of Limited Food Supply on an Unconfined Population

Cited by 51 publications

References 16 publications

Gene Flow in House Mice: Introduction of a New Allele Into Free‐living Populations

Gene Flow in House Mice: Introduction of a New Allele Into Free‐living Populations

The Role of Deme Size, Reproductive Patterns, and Dispersal in the Dynamics of t-Lethal Haplotypes

The effect of exploitation on the productivity of laboratory mouse populations

Contact Info

Product

Resources

About