Regulatory complexity of cellular differentiation in
Candida albicans
revealed through systematic screening of protein kinase mutants
Michael C. Lorenz
Abstract:A recent study in
mBio
reports the construction and preliminary screening of a library containing mutants of 99 of the 119 predicted protein kinases in
Candida albicans
(the majority of the remaining 20 are probably essential) (J. Kramara, M.-J. Kim, T. L. Ollinger, L. C. Ristow, et al., mBio e01249-24, 2024,
https://doi.org/10.1128/mbio.01249-24
). Using a quantitative competition assay in 10 conditions that represent nutritio… Show more
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