“…Previous studies have demonstrated differences between SP-A1 and SP-A2 that include both qualitative (i.e., functional, biochemical, and/or structure) [ 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 ] and quantitative (regulatory) changes [ 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ]. A recent study [ 60 ] examined SP-A genotype-dependent alterations in the bronchoalveolar lavage (BAL) proteome, and explored the effects of sex, infection, and ozone-induced oxidative stress on these changes.…”