Regulation of redox signaling mediated by H2O2 transporters

Serum-Derived Exosomes MicroRNA-923 and MicroRNA-523 Expression to Regulate Autophagy in Esophageal Squamous Cell Carcinoma

“…In turn, Hydrogen peroxide (H 2 O 2 ) can absorb large amounts of oxygen free radicals thereby inducing oxidative stress in cells, thus it is widely used as an apoptosis inducer [11] . Low concentrations of H 2 O 2 function as signaling molecules to regulate signaling pathways at different levels thereby affecting cell division and growth [12,13] . Nevertheless, when H 2 O 2 levels were excessive, the cell cycle would be blocked, which would further lead to apoptosis and autophagy [14,15] .…”