1971
DOI: 10.1159/000178222
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Regulation of Plasma Calcium in Man: The Influence of Parathyroid Hormone and Calcitonin

Abstract: The regulation of plasma calcium is usually attributed to variations in osteoclastic resorption of bone under the influence of parathyroid hormone. This hormone however increases tubular reabsorption of calcium and absorption of calcium from the gut. The actions of parathyroid hormone and calcitonin in man are reviewed and their probable role in calcium homeostasis outlined.

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Cited by 5 publications
(3 citation statements)
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“…Nuclear labeling with [''Hlthymidine at 1 h after injection was invariably confined to cells similarly located (Figs. 6,[8][9][10][11]. With [''Hlthymidine, the only cells labeled 1 h after injection in bone populations were classically described as osteoprogenitor cells (17,19).…”
Section: Suspected Targets In Calcifiedmentioning
confidence: 99%
See 1 more Smart Citation
“…Nuclear labeling with [''Hlthymidine at 1 h after injection was invariably confined to cells similarly located (Figs. 6,[8][9][10][11]. With [''Hlthymidine, the only cells labeled 1 h after injection in bone populations were classically described as osteoprogenitor cells (17,19).…”
Section: Suspected Targets In Calcifiedmentioning
confidence: 99%
“…bv, Blood vessel; ob, osteoblast . DISCUSSION Two major hormones, parathyroid hormone and calcitonin, are known to have antagonistic effects on the level of serum calcium (9,16) and consequently on the regulation of bone homeostasis. In this study we have prepared `25 I-labeled salmon calcitonin by a method known to preserve its biological activity (8,14,15).…”
Section: Warshawsky Et Almentioning
confidence: 99%
“…Since the first parathyroidectomy (PTX) for hyperparathyroidism (HPT) by Felix Mandl in 1925 and subsequent reoperation for recurrent disease [1], the full spectrum of primary HPT has tilted. The widespread use of multichannel analyzers and the breakthrough of the parathormone (PTH) radioimmunoassay [2] followed by the more accurate chemoluminescent assay [3] led to early recognition of more and more cases at an earlier stage of the disease, all treated by bilateral neck exploration, with identification of four or more parathyroid glands; there was a success rate of more than 95.0% [4][5][6] (97.6% in our experience) [7]. Successful PTX requires an experienced surgeon to find, recognize, and excise the abnormal parathyroid glands.…”
mentioning
confidence: 99%