Regulation of oviduct function in pigs by local transfer of ovarian steroids and prostaglandins: a mechanism to influence sperm transport

Hunter, Richard; Cook, B.; Poyser, N.L.

doi:10.1016/0028-2243(83)90264-2

Cited by 100 publications

(57 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the oviductal transfer of COCs together with 0.6 ml of FF aspirated in the immediate periovulatory period increased the in vivo fertilisation rate compared to those included in PBS medium (56.5 vs. 37.1%) and was similar to untreated controls (50.6%) [17]. This cited experimental data supports the proposition of Hunter et al [11,23] that an ovarian and local counter-current transfer of signals causes changes in sperm migration and fertilisation.…”

Section: Discussionsupporting

confidence: 84%

See 1 more Smart Citation

Experimental Evidence for the Influence of Cumulus-Oocyte-Complexes on Sperm Release from the Porcine Oviductal Sperm Reservoir

Brüssow

Torner

Rátky³

et al. 2006

Journal of Reproduction and Development

View full text Add to dashboard Cite

Abstract. In the pig, a temporal relationship is suggested between sperm release from the sperm reservoir (SR) and ovulation, but the mechanism(s) is still under discussion. In two experiments, the influence of transferred ova on the release of SR-spermatozoa at ovulation and the effect of supplementation with non-sulfated glycosaminglycan hyaluronan (HA) on embryo development and the number of accessory spermatozoa, respectively, were examined. PMSG/hCG primed ovectomized gilts that had previously received endoscopic low-dose insemination into the cranial uterine horn were used as an experimental model. After salpingectomy, tubal segments (ampulla, cranial, and caudal isthmus) were flushed and sperm numbers or respective accessory spermatozoa were counted. In Experiment 1, the distribution of the sperm population was altered in the presence of cumulus-oocyte-complexes (COCs). A higher proportion of spermatozoa was found after transfer of COCs into one oviduct in the ampulla and cranial isthmus segments compared with the controls (17.5 vs. 4.9%, p<0.05). In Experiment 2, the quality of the transferred ova and treatment influenced the presence of accessory spermatozoa. Transfer of COCs together with HA increased (p<0.05) the number of accessory spermatozoa compared with the other treatment groups and was similar to those in the "undisturbed" controls. No modifications were obtained regarding mean blastomere numbers (2.6 ± 0.2 to 3.1 ± 0.2). In summary, this study was demonstrated that cumulus-oocyte-complexes may be involved in triggering sperm release from the pig oviductal SR and that HA might be related to sperm release.

show abstract

Section: Discussionsupporting

confidence: 84%

“…shown that signals, such as pre-ovulatory follicular progesterone, are possibly involved [8][9][10] due to the transfer of follicular steroids, prostaglandins, and peptides via the subovarian plexus by a counter-current mechanism [11]. However, the involvement of follicular fluid (FF) in sperm release [12] has not been experimentally confirmed in pigs.…”

mentioning

confidence: 99%

Experimental Evidence for the Influence of Cumulus-Oocyte-Complexes on Sperm Release from the Porcine Oviductal Sperm Reservoir

Brüssow

Torner

Rátky³

et al. 2006

Journal of Reproduction and Development

View full text Add to dashboard Cite

show abstract

“…PGF 2a seems to form a special case, as the transfer was delayed for 20 min; this remains unexplained (McCracken et al 1972). A difference between the endogenous concentrations of steroids in the ovarian arterial blood and systemic blood was also found (Hunter et al 1983). Thus there seems to be little doubt that local counter-current transfer of regulatory substances underlies the normal function of the female reproductive system (Krzymowski 1992, Krymowski & Stefanczyk-Krymowska 2002.…”

Section: Transfer From Testis To Testis and To Epididymismentioning

confidence: 99%

Counter-current transfer in reproductive biology

Einer‐Jensen

Hunter²

2005

Reproduction

104

View full text Add to dashboard Cite

Heat and substances, including gases, steroids and peptide hormones, can pass from venous blood, interstitial fluid and lymph to the arterial blood; the process is called local counter-current transfer. It has been found in various reproductive organs in many animal species and in man: from the testis to the testis and epididymis; from the ovary to the ovary, tube and tubal corner of the uterus; from the tube and uterus to the ovary; from vagina to uterus; and even between brain blood vessels. Local transfer within the ovary has also been found. Local cooling that creates temperature gradients between organs or within an organ is one aspect of the transfer. Physiologically, the transfer also facilitates local feedback regulation of organ function in a process situated between general distribution of hormones through the systemic circulation and paracrine regulation. Counter-current transfer of drugs after local application opens up new possibilities for treatment.

show abstract

“…Arrest of spermatozoa in a pre-capacitated state with intact plasma and acrosomal membranes would clearly be beneficial for the phase of storage and preservation of subsequent fertilizing ability (Hunter & Nichol, 1983), as would location of this functional reservoir close to the site of fertilization. In the latter regard, the caudal region of the oviduct isthmus that appears to have evolved as a temporary storage site for viable spermatozoa is also a region of the duct exposed to high concentrations of ovarian follicular hormones due to a local counter-current transfer mechanism (Hunter, Cook & Poyser, 1983); its tissues can therefore be subjected to a form of preovulatory endocrine programming so that spermatozoa are activated and displaced to the site of fertilization at the ampullary-isthmic junction shortly before the eggs are released.…”

Section: Introductionmentioning

confidence: 99%

A preovulatory temperature gradient between the isthmus and ampulla of pig oviducts during the phase of sperm storage

Hunter¹,

Nichol²

1986

Reproduction

109

View full text Add to dashboard Cite

Summary. Fine thermistor probes positioned in each end of the same oviduct and connected to the same scale were used to measure temperature gradients in the lumen before and after spontaneous ovulation in normally-cyclic gilts. Readings were taken after full surgical closure of a mid-ventral incision and a subsequent period of stabilization, but whilst animals remained under general anaesthesia.A small but consistent difference in temperature was recorded between the proximal ampulla and distal isthmus of the same oviduct in each of 20 preovulatory gilts. In 10 of these animals that had not mated, the isthmus was a mean of 0\m=.\43\s=deg\Ccooler than the ampulla (range 0\ m=. \ 2\ p=n-\ 0\ m=. \ 7\ s=deg\ C whereas in 10 mated animals the isthmus was 0\m=.\69\s=deg\Ccooler (range 0\ m=. \ 2\ p=n-\ 1\ m=. \ 6\ s=deg\ C 3 animals in the latter group had within-oviduct differences of \ m=ge\ 1\s=deg\C. By contrast, in 12 animals that had recently ovulated, the isthmus was a mean of only 0\ m=. \ 1\ s=deg\ Ccooler than the ampulla; there was no measurable temperature gradient in 3 of the animals, whilst the isthmus was 0\ m=. \ 1\ s=deg\ C warmer in 2 animals. The preovulatory temperature differences are thought primarily to reflect the extent and activity of the vascular and lymphatic beds in the oviduct tissues and, together with specific chemical microenvironments, may facilitate the relatively prolonged period of sperm storage in the distal portion of the isthmus.

show abstract

Regulation of oviduct function in pigs by local transfer of ovarian steroids and prostaglandins: a mechanism to influence sperm transport

Cited by 100 publications

References 21 publications

Experimental Evidence for the Influence of Cumulus-Oocyte-Complexes on Sperm Release from the Porcine Oviductal Sperm Reservoir

Experimental Evidence for the Influence of Cumulus-Oocyte-Complexes on Sperm Release from the Porcine Oviductal Sperm Reservoir

Counter-current transfer in reproductive biology

A preovulatory temperature gradient between the isthmus and ampulla of pig oviducts during the phase of sperm storage

Contact Info

Product

Resources

About