Regulation of mitochondrial dysfunction by estrogens and estrogen receptors in Alzheimer's disease: A focused review
Shokouh Arjmand,
Mehran Ilaghi,
Ali Karimi Sisakht
et al.
Abstract:Alzheimer's disease (AD) is a neurodegenerative disorder that primarily manifests itself by progressive memory loss and cognitive decline, thus significantly affecting memory functions and quality of life. In this review, we proceed from the understanding that the canonical amyloid‐β hypothesis, while significant, has faced setbacks, highlighting the need to adopt a broader perspective considering the intricate interplay of diverse pathological pathways for effective AD treatments. Sex differences in AD offer … Show more
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