Abstract:To investigate the targeting mechanism of long-chain non-coding RNA NEAT1 (LncRNA NEAT1) for microRNA-199a-5p (miR-199a-5p), to regulate hypoxia/reoxygenation (H/R) in myocardial cell impairment. Rat cardiomyocytes were cultured in vitro and divided into the: Con group, H/R group,
H/R + si-NC group, H/R + si-NEAT1 group, H/R + miR-NC group, H/R + miR-199a-5p group, H/R + si-NEAT1 + anti-miR-NC group, and H/R + si-NEAT1 + anti-miR-199a-5p group. Levels of endocellular NEAT1 and miR-199a-5p were evaluated with … Show more
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