Regulation of immune response against third-stage Gnathostoma spinigerum larvae by human genes
Pattarasuda Puasri,
Wilanee Dechkhajorn,
Paron Dekumyoy
et al.
Abstract:BackgroundGnathostomiasis is an important zoonosis in tropical areas that is mainly caused by third-stage Gnathostoma spinigerum larvae (G. spinigerum L3).ObjectivesThis study aimed to prove whether G. spinigerum L3 produces extracellular vesicles (EVs) and investigate human gene profiles related to the immune response against the larvae.MethodsWe created an immune cell model using normal human peripheral blood mononuclear cells (PBMCs) co-cultured with the larvae for 1 and 3 days, respectively. The PBMCs were… Show more
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