“…and Aufrère, lack of effect was partly due to the induction of enzymes of amino acid catabolism in the liver (Harper, 1965 ;Szepesi and Freedland, 1968 ;Pestana, 1969 ;Mauron, Mottu and Spohr, 1973 ;Yanagi, Campbell and Potter, 1975) and to an increase in the capacity for ureogenesis (Schimke, 1962). On the contrary, even after a 4-week adaptation period, the ingestion of a protein meal fed separately can induce an important increase in liver protein synthesis (over 3-fold within 1 h) (Lardeux, Bourdel and Girard-Globa, 1978 (De Rosa and Swick, 1975). Tyrosine aminotransferase was thought to be of interest since, like ornithine decarboxylase, it has a short half-life and is thus sensitive to variations in protein synthetic activity.…”