Abstract:Granulocyte colony-stimulating factor (G-CSF) is a naturally occurring glycosylated protein that was originally identified as a granulopoietic growth factor. It has been shown that G-CSF stimulates the proliferation and maturation of neutrophil precursor cells as well as increases such neutrophil functions as chemotaxis, phagocytosis, and bactericidal activity. G-CSF has drawn recent attention as a therapeutic drug for sepsis, because studies show that G-CSF not only selectively stimulates the proliferation of… Show more
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