Regulation of dispersion/aggregation of phosphonium-presenting iron oxide nanoparticles by anion exchange

Tanaka, Kazuo; Narita, Asako; Suzuki, Kentaro; Chujo, Yoshiki

doi:10.1080/15685543.2012.762862

Cited by 3 publications

(3 citation statements)

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“…We synthesized three types of the phosphonium-presenting SPIOs as shown in Figure 8. 55 To inhibit undesired interaction between the ionic species and the surface of the nanoparticles and reinforce the stability of the phosphonium cation, we introduced the silica layer at the surface of the SPIO. NP1 and NP2 are covered with the bilayer with or without the silica layer at the surface between the SPIO core and the inside layer, respectively.…”

Section: Cluster Formation Of Spios By Employing Ionic Liquid Chemistrymentioning

confidence: 99%

“…The dispersion states of the phosphonium-presenting SPIOs were monitored during anion exchange. 55 To the aqueous dispersions of phosphonium bromide-presenting SPIOs, NP1 and NP2, NaCl and potassium bis(trifluoromethanesulfonyl)amide (KTFSA) were added, respectively ( Figure 9). By adding NaCl, all SPIOs maintained the dispersion states.…”

Section: Cluster Formation Of Spios By Employing Ionic Liquid Chemistrymentioning

confidence: 99%

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Design of functionalized nanoparticles for the applications in nanobiotechnology

Tanaka

Chujo

2014

Advanced Powder Technology

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Nanoparticles have attracted attention as a scaffold to obtain smart biomaterials because of several advantages: Firstly, the biodistribution of the nanoparticles can be modulated by changing the size of the particles. For example, as we presented in this paper, silica-based nanoparticles are versatile materials for designing functional bioprobes and the vesicles for drug delivery because of their high stability and the flexibility in the modification. Because various size and surface-modified silica nanoparticles can be readily prepared, we can deliver drugs or other bioactive materials to the target sites by loading onto the nanoparticles with the size effects on the distribution. In particular, nanoparticles in the range of 20 nm to 400 nm in diameter show tumor-selective integration known as the enhanced permeability and retention (EPR) effect. 1-7 Therefore, the site-specific delivery can be realized based on the preprogrammed designs. Secondly, the local concentrations of the loaded drugs can be readily enhanced. In the case of the drugs with small molecular weights, the drug concentrations could be lowered by the diffusion. On the other hand, since the nanoparticles have better retention ability than those of small molecules, it is relatively easy to keep the local concentration to receive enough drug efficiency. In addition, if the nanoparticle can slowly release the loaded drugs, the sustained release system can be readily realized. Thirdly, the diverse properties can be obtained not only originated from the intrinsic properties of the component elements or the surface modification but also from the nano-sized effects of the particles. For example, the nanoparticles composed of ferromagnetic iron oxide show similar behaviors, called superparamagnetism, to the paramagnetic materials such as no hysteresis and no residual magnetization. 8,9 These materials are used as a conventional contrast agent in magnetic resonance imaging (MRI). In the case of gold nanoparticles, the absorption bands in the visible region can be observed. Various kinds of biosensors have been invented based on the gold nanoparticles. The nanoparticles composed of semiconductor materials called as quantum dots show various emission colors depended on their diameters. 10-13 Based on these characteristics derived from the size effects, unique optical bioprobes have been developed. In this review, we survey the functionalized nanoparticles for the application in nanobiotechnology. Our recent studies on the development of bioprobes or bio-related materials with the series of nanoparticles composed of iron oxide, silica and gold are mainly introduced. The typical synthetic procedures are also described in the latter part. Superparamagnetic iron oxide MR sensors for biomolecules Initially, we present the superparamagnetic iron oxide (SPIO)-based contrast agents in magnetic resonance imaging (MRI). MRI is one of the powerful and conventional diagnostic tools in modern clinical medicine for the 3D visualization inside vital bodies with high res...

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Section: Cluster Formation Of Spios By Employing Ionic Liquid Chemistrymentioning

confidence: 99%

Section: Cluster Formation Of Spios By Employing Ionic Liquid Chemistrymentioning

confidence: 99%

Design of functionalized nanoparticles for the applications in nanobiotechnology

Tanaka

Chujo

2014

Advanced Powder Technology

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“…Recently, we reported the modulation of dispersibility of the IL-modied metal nanoparticles. 4,5 By the anion exchange of ILs at the surface of the particles, the compatibility with solvent molecules was greatly changed. As a result, the dispersion/aggregation of the nanoparticles can be controlled under mild conditions.…”

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Adamantane ionic liquids

et al. 2014

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65 adamantane. Thereby, adamantane should be a good example as a scaffold to evaluate the steric core effect on the thermal properties of ion pairs. Herein, we report the characteristic thermal properties of the adamantane-tethered ion salts (Figure 1). The series of ion salts with adamantane carboxylates and imidazolium cations were 70 prepared. The influence of chemical structures of adamantanebased salts on melting temperatures and thermal stability was investigated with various numbers of ion pairs around the

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Rapid heat generation under microwave irradiation by imidazolium-presenting silica nanoparticles

Okada

Kajiwara²,

Tanaka

et al. 2013

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Regulation of dispersion/aggregation of phosphonium-presenting iron oxide nanoparticles by anion exchange

Cited by 3 publications

References 10 publications

Design of functionalized nanoparticles for the applications in nanobiotechnology

Design of functionalized nanoparticles for the applications in nanobiotechnology

Adamantane ionic liquids

Rapid heat generation under microwave irradiation by imidazolium-presenting silica nanoparticles

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