Regulation of collagen deposition in the trout heart during thermal acclimation

Johnston, Elizabeth F.; Gillis, Todd E.

doi:10.1016/j.crphys.2022.02.004

Cited by 8 publications

(9 citation statements)

References 113 publications

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“…Zhao et al 226 reported that feed restriction enhanced collagen deposition and shear force in the muscle of lambs, corresponding to the upregulation of p38 MAPK signalling pathway. Also, studies of cultured trout cardiac fibroblasts reported that collagen turnover can be controlled, at least partly, by MAPK signalling, indicating its conserved function in vertebrates 227 …”

Section: Strategies To Regulate Texture Characteristics In Aquaculturementioning

confidence: 99%

The flesh texture of teleost fish: Characteristics and interventional strategies

Wang,

Qiao,

Zhang

et al. 2023

Reviews in Aquaculture

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With the growing demand of consumers for high‐quality aquatic products, controlling the harvest quality of farmed fish is becoming increasingly important in aquaculture industry. The texture is a sensory property that covers a group of attributes, such as firmness, tenderness, chewiness, adhesiveness, resilience, etc., which greatly determine consumers' perception and satisfaction for flesh products. Regarding texture quality, extensive research has been conducted in recent decades based on its related theories, influencing factors, and intervention strategies. However, the information available is largely scattered and disjointed. Essentially, flesh texture is mainly determined by the collective contribution of three major muscle components: muscle fibres, intramuscular connective tissue, and intramuscular fat. Therefore, changing these components in living animals through nutritional and management factors has the potential to modulate texture quality. Here, we briefly introduced the features and development of the three muscle components mentioned above, particularly their potential contributions to texture quality of fish flesh. Exciting promises to manipulate flesh texture through dietary intervention, feed restriction, and exercise training were also discussed. To ensure their applications in large‐scale aquaculture facilities, specific considerations of these regimens should be incorporated in experimental design parameters, including the species and age of fish, research system, experiment duration, and exercise intensity. Finally, the existing challenges and limitations of fish texture studies were presented, along with some viewpoints about current work and future directions of this field.

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Section: Strategies To Regulate Texture Characteristics In Aquaculturementioning

confidence: 99%

The flesh texture of teleost fish: Characteristics and interventional strategies

Wang,

Qiao,

Zhang

et al. 2023

Reviews in Aquaculture

View full text Add to dashboard Cite

show abstract

“…However, the known pathways are shared by both organs. Of prime interest are the elegant publications by Johnston and Gillis (2022) who studied rainbow trout and zebrafish [e.g., (Johnson et al, 2014)] and noted that the increase in deposited collagen, a major determinant of elasticity/stiffness of the extracellular matrix in these fish, is reversible and the collagen content changes in response to thermal (cold vs. warm) acclimation in order to maintain ventricular performance as the water temperature varies with the seasons. Other studies (Jørgensen et al, 2014;Keen et al, 2016) show comparable adaptive responses, e.g., in ectothermic vertebrates the collagen content decreases as environmental temperature increases.…”

Section: Cellular Signaling Associated With Vascular and Ventricular ...mentioning

confidence: 99%

“…Recently acclimatory homeostasis has been attributed to epigenetic mechanisms such as post translational histone modifications ( Tetievsky and Horowitz, 2010 ) and ( Horowitz, 2010 ; Horowitz, 2017 ). The correlation between physiology and cell signaling/molecular biology in heat-acclimation highlights the pathways common to this phenomenon in the global vascular response and the heart, e.g., ( Haddad and Horowitz, 1999 ; Assayag et al, 2010 ; Yacobi et al, 2014 ; Brunt et al, 2016 ; Alexander-Shani et al, 2017 ; Johnston and Gillis, 2022 ) and others as detailed in Sections 5 .…”

Section: Long- But Not Short-term Acclimation Increases Cardioprotectionmentioning

confidence: 99%

“…The ECM is involved in many aspects of cardiovascular physiology and pathology (e.g., ( Bloksgaard et al, 2018 ). Thus, based on the knowledge of cell signaling in mammals (humans, rodents) Johnston and Gillis (2022) examined changes in the ECM in thermally acclimated trout and zebrafish and demonstrated that the TGF β1-SMAD pathway plays a major role. In a human translational study on thermal therapy Lucas et al (2018) demonstrated that endothelial cells share similar pathways, involving the NO induced TGF β1-SMAD pathway.…”

Section: Cellular Signaling Associated With Vascular and Ventricular ...mentioning

confidence: 99%

“…The elegant review by Frangogiannis (2019), emphasizes the importance of the ECM (extracellular matrix) network in maintaining cardiac homeostasis, by providing structural support, facilitating force transmission and transducing key signals to cardiomyocytes, vascular cells, and interstitial cells in health and disease. This cellular signaling (Section 5) is noted in endotherms and ectotherms (Johnston and Gillis, 2022). The timing of these processes upon exposure to chronic heat has not been studied in humans.…”

Section: Introductionmentioning

confidence: 99%

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Vascular compliance and left ventricular compliance cross talk: Implications for using long-term heat acclimation in cardiac care

Horowitz

Hasin²

2023

Front. Physiol.

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1) The first evidence of the beneficial impact of Long-Term-Heat-Acclimation (LTHA) on cardio-vascular compliance was the positive inotropic response and improved left ventricular (LV) compliance noted when isolated hearts from LTHA rats were studied. Human echo study demonstrates that passive HA affects the right ventricle and the atria as well. 2) There is a cross-talk between vascular and cardiac compliance. Vascular compliance per se is defined by central venous pressure—Blood volume relationship—Global Vascular Compliance (GVC). It is determined by the sum of the vascular compliance of the vessels in every organ in any physiological state, varies with LTHA and thus influences cardiac performance. LTHA improves endothelial function, increases NO (nitric oxide) production, in-turn stimulating alterations in ECM (extracellular matrix) via the TGF β1-SMAD pathway. 3) LTHA is associated with transformation from fast to slow myosin, heat acclimation ischemic/hypoxic cross-tolerance and alterations in the extracellular matrix. 4) A human translational study demonstrated improved LV compliance following bypass surgery in LTHA subjects compared to controls. 5) Diastolic dysfunction and the impact of comorbidities with vascular and non- vascular origins are major contributors to the syndrome of heart failure with preserved ejection function (HFPEF). Unfortunately, there is a paucity of treatment modalities that improve diastolic dysfunction. 6) In the current mini-review we suggest that LTHA may be beneficial to HFPEF patients by remodeling cardiac compliance and vascular response.

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The oldies are the goodies: 30 years on “The Heart” still sets the pace

Shiels

2023

Fish Physiology

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Regulation of collagen deposition in the trout heart during thermal acclimation

Cited by 8 publications

References 113 publications

The flesh texture of teleost fish: Characteristics and interventional strategies

The flesh texture of teleost fish: Characteristics and interventional strategies

Vascular compliance and left ventricular compliance cross talk: Implications for using long-term heat acclimation in cardiac care

The oldies are the goodies: 30 years on “The Heart” still sets the pace

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