Regulated exocytosis from astrocytes: a matter of vesicles?

Abstract

Ultrastructural evidence using EMTo date, the best way to study cellular ultrastructure from a morphological level, is by far Electron Microscopy (EM). In fact, by increasing resolution limit by a factor of two compared to fluorescence microscopy, it is the only technique capable of unequivocally identify nanometer-sized structures (Knott and Genoud, 2013;Boges et al., 2020). This includes small, astrocytic perisynaptic astrocytic processes (PAPs), and their organelles.