Regularities in the Spectra of Molecular Complexes

McConnell, Harden M.; Ham, Joe S.; Platt, John R.

doi:10.1063/1.1698626

Cited by 254 publications

(56 citation statements)

References 12 publications

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“…It has been reported that the ionization potential of the electron donor may be correlated with the charge transfer transition energy of the complex. 32 Comparison of the transition energies of the CTC in different solvents with the I p values of the electron donors in the corresponding solvents forming the complex reveals a regular relationship, which is in accord with the results obtained by McConnel et al 33 Further evidence for the nature of CT-interaction in the present systems is the calculation of the dissociation energy (W) of the charge transfer excited state of the complex in different solvents. Hence the dissociation energies of the complex were calculated from their CT-energy (hν CT ), I p and E A of the acceptor using the empirical relation given in eqn (5).…”

Section: Ionization Potential Of the Donorsupporting

confidence: 88%

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Spectroscopic studies of charge transfer complexes of meso‐tetra‐p‐tolylporphyrin and its zinc complex with some aromatic nitro acceptors in different organic solvents

El‐Zaria

Genady

2007

Applied Organom Chemis

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Section: Ionization Potential Of the Donorsupporting

confidence: 88%

“…Hence the dissociation energies of the complex were calculated from their CT-energy (hν CT ), I p and E A of the acceptor using the empirical relation given in eqn (5). 33 hν…”

Section: Ionization Potential Of the Donormentioning

confidence: 99%

Spectroscopic studies of charge transfer complexes of meso‐tetra‐p‐tolylporphyrin and its zinc complex with some aromatic nitro acceptors in different organic solvents

El‐Zaria

Genady

2007

Applied Organom Chemis

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“…The ionization potential Ip of 2T2T can be evaluated (Ip = 8.75 ± 0.01 e.v.) using the relationships between the ionization potential and maxima frequency of the charge transfer band as described by McConnel and Hastings (7,8). …”

Section: Chemical Experimentsmentioning

confidence: 99%

Sites of Action of 2-Thiazoline-2-Thiol on Biogenesis of Thyroid Hormones.

et al. 1992

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ABSTRACT-2-Thiazoline-2-thiol is an antithyroid agent that strongly reduces thyroid hormone levels. Synthesis of these hormones is catalyzed in vivo by thyroid peroxidase. The interaction of this drug with molecular iodine and its effect on peroxidase activity were investigated. Iodine and 2-thiazoline-2-thiol form a complex of the charge transfer type of 1:1 stoichiometry characterized by a formation constant of 2,5271-mole-1 at 20°C. This drug was found to inhibit both horseradish peroxidase and lactoperoxidase (used as a model of thyroid peroxidase) in a competitive manner, giving inhibition con stants of 5.7 mM and 0.13 mM, respectively. T3 and T4 levels were reduced significantly after a three-week administration of this drug to a group of 10 rats. Histological ex amination of the thyroid gland showed the presence of a cylindrical epithelium, which is indicative of hyperactivity of the gland. The results indicated that 2-thiazoline-2-thiol acts on both molecular iodine and thyroid peroxidase.Synthetic antithyroid agents are thought to exert their action on thyroid peroxidase, the enzyme responsible for the oxidation of iodides and the coupling of iodotyrosines to iodothyronines (1, 2). We showed that they may also interact with molecular iodine (3). Iodine is complexed by the drug, and thus be comes unavailable for synthesis of thyroid hor mones. A drug which has activity towards TPO and which can complex molecular iodine will thus have particularly strong antithyroid activity. In the present study, we investigated the action of the antithyroid drug 2T2T (4), which has a partially hydrogenated thiazole nucleus. This drug also contains a thiol group, which is also found in MMI, a powerful anti thyroid agent. We also tested action of 2T2T in vivo in the rat to find out whether the com bined actions on peroxidase and iodine did in fact confer strong antithyroid activity.

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“…The comparison of the position of absorption bands with the ionization potential of the donor was found by McConnell, Han and platt [16,17] to facilitated by a equation (6) that was linear for ionization potential between (7-13) eV. Where (hνCT) is transition energy for CT band, (C1 and C2) are physical constant parameters of electron acceptor in the solvent (C1=0.51eV and C2=1.27eV 2 in ethanol solvent) [7,11].…”

Section: Resultsmentioning

confidence: 99%

Spectroscopic and Thermodynamic Studies of Charge- Transfer Complexes Formation Between Cytosine, Uracil and Thymine With Electronic Accepters

Al-Thib

Al-Alwi

Eliwe

2013

JNUS

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Charge-transfer complexes of 2, 3-dichloro-5, 6-dicyano-1, 4-benzo quinone (DDQ), 2, 3, 5, 6-tetrabromo-1, 4-benzoquinone (Bromanil) and iodine as electronic acceptors with cytosine, uracil and thymine as electronic donors were studies and their electronic spectra were recorded. In each case one charge-transfer (CT) band was observed and recorded. These spectroscopic investigation make in ethanol solvent at four different temperatures (20, 25, 30 and 35°C). The values of equilibrium constant (KCT), molar extinction coefficient (εCT (, absorption band energy of chargetransfer complexes (hνCT) and the dissociation energy of the charge-transfer complexes excited state (W) were calculated and studied with discussed. The ionization potential of the donors (IP) were calculated and discussed from the charge-transfer complex band lowest energy. Thermodynamic parameters i. e. change in standard free energy (ΔG°), change in standard entropy (ΔS°) and change in standard enthalpy (ΔH°) for all these CT complexes were also calculated and discussed.

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Regularities in the Spectra of Molecular Complexes

Cited by 254 publications

References 12 publications

Spectroscopic studies of charge transfer complexes of meso‐tetra‐p‐tolylporphyrin and its zinc complex with some aromatic nitro acceptors in different organic solvents

Spectroscopic studies of charge transfer complexes of meso‐tetra‐p‐tolylporphyrin and its zinc complex with some aromatic nitro acceptors in different organic solvents

Sites of Action of 2-Thiazoline-2-Thiol on Biogenesis of Thyroid Hormones.

Spectroscopic and Thermodynamic Studies of Charge- Transfer Complexes Formation Between Cytosine, Uracil and Thymine With Electronic Accepters

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