Regression of ventral striatum hypometabolism after calcium/calcitriol therapy in paroxysmal kinesigenic choreoathetosis due to idiopathic primary hypoparathyroidism

The thalamic ultrastructural abnormalities in paroxysmal kinesigenic choreoathetosis: a diffusion tensor imaging study

“…The mean age at initial onset was 11.7 ± 3.1 (range [8][9][10][11][12][13][14][15][16][17] years, and the mean disease duration was 6.9 ± 5.1 (range [1][2][3][4][5][6][7][8][9][10][11][12][13][14] years. The confirmation of PKC was based on the diagnostic criteria of Kertesz [14].…”

“…There are not conventional magnetic resonance imaging (MRI) abnormalities in patients with idiopathic PKC. The pathophysiology of PKC may involve ion channel dysfunction [3] or abnormalities in the basal ganglia-thalamocortical circuits [4][5][6], but it remains unclear.…”

Pregabalin Resolves Refractory Aparathyroid Paroxysmal Kinesigenic Choreoathetosis

“…1 This could be due to hypometabolism of the ventral putamen and inferior caudate due to hypocalcemia. 2 Choreoathetosis has been classically treated with classic or atypical antipsychotics, most of which have the potential of causing tardive dyskinesia, which is refractory to treatment.…”

Effect of basal ganglia calcification on its glucose metabolism and dopaminergic function in idiopathic hypoparathyroidism

“…Reduction in 18 F-FDG uptake was earlier reported in isolated case studies of patients with BGC with IH, postsurgical hypoparathyroidism and Fahr's disease without hypoparathyroidism. [13][14][15][16] Interestingly, unlike, glucose metabolism, presence of BGC did not affect the dopaminergic function of the basal ganglia. To the best of our knowledge, there is no published study assessing dopaminergic function of the basal ganglia in IH to compare results of the present study.…”