Regression of Left Ventricular Hypertrophy Under Ramipril Treatment Investigated by Nuclear Magnetic Resonance Imaging

Eichstaedt, H.; Danne, O.; Langer, M.; Cordes, Michael; Schubert, Charlotte; Félix, R.; Schmutzler, H

doi:10.1097/00005344-198900133-00019

Cited by 33 publications

(7 citation statements)

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“…CMR is the best technique for assessing LV mass, 147,286 and following its progression over time (both for research trials [287][288][289][290] and for clinical patients), because of excellent interstudy reproducibility. 53,149,163 Left ventricular non-compaction This condition has become more recognised, 291 and appears to have autosomal dominant inheritance.…”

Section: Left Ventricular Hypertrophymentioning

confidence: 99%

Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?

Pennell

Sechtem

Higgins

et al. 2004

European Heart Journal

690

350

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Section: Left Ventricular Hypertrophymentioning

confidence: 99%

Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?

Pennell

Sechtem

Higgins

et al. 2004

European Heart Journal

690

350

View full text Add to dashboard Cite

“…CMR is the best technique for assessing LV mass (Myerson et al, 2002a;Myerson et al, 2002b), and following its progression over time (both for research trials (Brull et al, 2001;Eichstaedt et al, 1989;Hoffman et al, 2001;Myerson et al, 2001) and for clinical patients), because of excellent (Bellenger et al, 2000b;Bottini et al, 1995;Grothues et al, 2002).…”

Section: Left Ventricular Hypertrophymentioning

confidence: 99%

Clinical Indications for Cardiovascular Magnetic Resonance (CMR): Consensus Panel Report #

Pennell

Sechtem

Higgins

et al. 2004

J Cardiovasc Magn Reson

290

206

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“…In addition to lowering arterial blood pres sure, ACE inhibitors may also cause regres sion of left ventricular hypertrophy (LVH) in man [1][2][3][4][5] and experimental animals [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Left-Ventricular Hypertrophy in the Spontaneously Hypertensive Rat: Effect of ACE Inhibitors on Ultrastructural Morphology

et al. 1994

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The ACE inhibitors cilazapril and captopril were administered at 10 and 100 mg/day, respectively, to spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto rats (WKY) from the 12th to the 22nd week of life. Both drugs produced statistically significant reductions in systolic and diastolic blood pressure, left-ventricular mass and index of left-ventricular hypertrophy in SHR. After cilazapril treatment, the morphology of SHR cardiocytes became similar to that in untreated normotensive rats, while in captopril-treated rats, myofibrils were disarranged, obliquely oriented and smaller than normal, with areas of electron-transparent sarcoplasm separating the myofibril bundles; mitochondria were also altered. In WKY rats, we observed no statistically significant changes in blood pressure, ventricular weight and hypertrophy index between the two drugs; however, there were different effects of the two drugs on the ultrastructural morphology of the myocardium. These observations suggest that these two molecularly dissimilar ACE inhibitors act differently at the tissue level despite similar effects on blood pressure and left-ventricular mass.

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Regression of Left Ventricular Hypertrophy Under Ramipril Treatment Investigated by Nuclear Magnetic Resonance Imaging

Cited by 33 publications

References 0 publications

Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?

Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report?

Clinical Indications for Cardiovascular Magnetic Resonance (CMR): Consensus Panel Report #

Left-Ventricular Hypertrophy in the Spontaneously Hypertensive Rat: Effect of ACE Inhibitors on Ultrastructural Morphology

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