Regression formulae for predicting hematologic and liver functions from years of exposure to cement dust in cement factory workers in sokoto, nigeria

Mojiminiyi, F.B.O.; Merenu, I.A.; Njoku, C.O.; Ibrahim, Moustafa

doi:10.4314/ajbr.v10i3.50640

Cited by 6 publications

(6 citation statements)

References 6 publications

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“…The results are in agreement with (Mojiminiyi et al, 2007) who stated that the ALP activity increased proportionally with exposure time to cement dust in Sokoto Cement Factory-Nigeria and the highest activity was the Crusher, Cranes and Mills departments, also agree with other investigators (Struzak-Wysokinska et al, 1990) where the activity of ALP in workers exposed to cement dust was very high.…”

Section: Alpsupporting

confidence: 93%

Effect of Cement Pollution on some Biochemical Parameters in the Blood Serum of Hamam AL-Alil Cement Factory Workers

Al-Hayali¹

2009

RJS

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Long time exposure to cement industry pollution leads to several health problems. This study was designed to investigate the effects on 55 workers which were divided into groups according to the departments of Hamam AL-Alil Cement Factory-Iraq. The biochemical parameters included in the study are: calcium, zinc, lactate dehydrogenase, alkaline phosphatase, acid phosphatase, glutathione and malonaldehyde.The results showed that there was a significant increase in calcium, lactate dehydrogenase, alkaline phosphatase, acid phosphatase and malonaldehyde in workers serum which increased with increasing exposure time. The results also showed a significant decrease in glutathione and zinc in workers serum which increased with increasing exposure time in all factory department.

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Section: Alpsupporting

confidence: 93%

Effect of Cement Pollution on some Biochemical Parameters in the Blood Serum of Hamam AL-Alil Cement Factory Workers

Al-Hayali¹

2009

RJS

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“…Elevated levels of platelet count were observed in workers exposed to quarry dust. Findings of this study in agreement with Mojiminiyi 25 and similarly reported among the cement dust exposed workers in Nigeria. These significant depletions and elevated levels of haematological parameters clearly evidenced and revealed that the granite quarry dust could alter the cell walls of blood cells.…”

Section: Resultssupporting

confidence: 92%

Hematological Alterations Among Quarry Workers Exposed to Granite Dust in Thailand

M¹

2020

Int Res J Pharm

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The objective of this study is Granite quarry dust predominantly present at quarry sites. Exposure to quarry dusts is a major concern to the quarry workers and human beings. Lethal dust particles are detrimental to human's health. Hence, it may be accountable for hematological alterations in exposed community. This paper is a first to investigate the alterations of hematological parameters and to mimic silica dust implications in exposed and control workers. A total 200 subjects were selected randomly and grouped as experimental (N = 100) and control (N = 100). Blood samples were collected and used for hematological analysis. The study indicates that 84% of the quarry workers have 12-17 years of exposure to the quarry dust. Significant alteration was observed among selected hematological profile of exposed workers when compared with their control groups. The levels of total leukocytes (TLC) increased significantly (P < 0.0001) in both the groups exposed to quarry dust. Results of this study indicate that the quarry dust particles insist inflammation in humans. A significant depletion was observed in red blood cells (RBC) in both exposed groups. Declined levels of red blood cells could be due to inflammation. Increased levels of eosinophils were observed in exposed group. Analysis of hematopoietic system alterations in quarry dust exposed workers are crucial to mimic the health effects of quarry dust, as biomarkers of quarry dust exposure, inventing a better and easy diagnosis develop preventive standards and to measure epidemiological surveillance. Granite quarry management should take initiative steps to frequent monitoring of their quarry workers.

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“…ALP levels increased in a proportional way with exposure time (Table 3). The results are in agreement with (Mojiminiyi et al, 2007) (31) who stated that the ALP activity of cement workers proportionally increased with time exposure to dust. Increasing ALP activity might be due to exposure to heavy metals either by direct inhalation of suspended dust particles in air, dermal contact or indirect ingestion.…”

Section: Occupationalsupporting

confidence: 92%

Neopterin as assessment marker for susceptibility of silicosis in dental technician

El-Sharkawy

Ahmed²

2016

Biochemistry Letters

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Background: Dental technician expose to large amounts of crystalline silica that increase their risk of developing silicosis. Neopterin are produced upon stimulation with the cytokine interferon-γ. Neopterin is produced by activated monocytes, macrophages, and dendritic cells upon stimulation by interferon gamma produced by Tlymphocytes. Neopterin production provides prognostic information in patients with autoimmune diseases. Objective: Assessment of serum neopterin, inflammatory cytokines, enzyme activities and trace elements in smokers and non smokers dental technicians and to compare them with the corresponding levels in a control group. Subjects and Methods: Serum was examined in 45 dental technician, 15 subjects as a control group and 30 subjects exposed to silica. The surveyed dental technician were divided into three groups: 1 st group (control group), 2 nd group (smokers dental technician) and 3 rd group (non smokers dental technician). Serum neopterin, some trace elements, LDH, ALP, ACP, TNF-α, and IL-8 were determined. Result: Higher levels of neopterin were established in smokers dental technician exposed to crystalline silica (16.48 ng/ml) by comparison with non smokers dental technicians (9.85 ng/ml) and the control group (4.24 ng/ml). Significant increase in the levels of silica, calcium, copper, enzymatic activities, TNF-α, IL8 and a significant decrease in Zn levels in serum of smokers subject compared with both non smokers and control subjects. Conclusion: Research on biomarkers for silicosis is still at its nascent stage. The concentration of serum neopterin could be used as a biomarker in the diagnostic criteria for silicosis moreover it is suitable for introduction into the routine clinical laboratory practice.

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Regression formulae for predicting hematologic and liver functions from years of exposure to cement dust in cement factory workers in sokoto, nigeria

Cited by 6 publications

References 6 publications

Effect of Cement Pollution on some Biochemical Parameters in the Blood Serum of Hamam AL-Alil Cement Factory Workers

Effect of Cement Pollution on some Biochemical Parameters in the Blood Serum of Hamam AL-Alil Cement Factory Workers

Hematological Alterations Among Quarry Workers Exposed to Granite Dust in Thailand

Neopterin as assessment marker for susceptibility of silicosis in dental technician

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