Abstract:A regioselective and convenient methodology was developed to synthesize heterocyclic derivatives, bearing imidazole, piperidines, and azepines rings. The N‐arylnitrones derived from 3‐formylchromones were selected to react with heterocyclic ketene aminal to furnish the structurally attractive and pharmacologically important fused ring heterocycles. The N‐arylnitrone moiety of 3‐formylchromone was used to activate the formyl group for regioselective fused ring heterocycles synthesis, whereas, the effect of subs… Show more
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