The use of supported Cu complex on mesoporous as a novel, efficient, heterogeneous, reusable and green catalyst for the synthesis of spiro-dihydrofuran derivatives is reported. This methodology is effective for the reaction of dimedone with a wide range of aldehyde in the presence of BrCN and triethylamine.The structure of catalyst was characterized by different techniques such as EDX, SEM, TGA, ICP-OES, XRD, TEM, FT-IR, and BET. The recycled nanocatalyst was used at least five times with no significant loss of its activity.