Triepoxides were synthesized for the first time in high yields (80-85%) by oxidation
of substituted bicyclo[4.2.2]deca-2,4,7,9-tetraenes, bicyclo[4.2.2]deca-2,4,7-trienes,
and tricyclo[9.4.2.02,10]heptadeca-2,12,14,16-tetraene with an excess of m-chloroperbenzoic
acid. The structures of the epoxy derivatives were reliably proved using modern
spectral methods and X-ray diffraction analysis. A high antitumor activity in vitro was
found for triepoxides against the Jurkat, K562, U937 tumor cell lines and normal fibroblasts.