Regional wall motion analysis: an important tool to study pharmacologic agents in the absence of systemic effects

Quantitative Evaluation of Left Ventricle Performance from Two Dimensional Echo Images

“…Most of those are derived from the septal‐free wall diameter and anterior‐posterior diameters measured in the short axis that only gives the idea about the deformity at that cross section and also it will not significantly differ if both the diameters vary at equal rate. Few others are derived from volumes or area of cross section then normalizing it to any of the diameters 11 or from the centre of mass, 8 where the results are not significant. These problems are addressed by the ER that is derived from the endocardial length and the eccentricity index of LV that is of order two.…”

“…Two‐dimensional (2D) echocardiography, the ideal noninvasive method for visualizing the change in ventricular structure and function, calls for the opportunity to develop new methods that are able to provide information not only on the ventricular function but also on its shape. Earlier studies demonstrate that functional 1–5 and morphological analysis 6 of LV are used to quantify the global LV dysfunction 7,8 and wall motion analysis for regional dysfunction 9–11 . Important results have been obtained on the topography of expansion and shape distortion of LV.…”