Regional ventilation in cystic fibrosis measured by electrical impedance tomography

Zhao, Zhanqi; Fischer, Rainald; Frerichs, Inéz; Müller-Lisse, Ullrich; Möller, Knut

doi:10.1016/j.jcf.2012.03.011

Cited by 75 publications

(57 citation statements)

References 28 publications

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“…To date it has primarily been used in mechanically-ventilated patients to control and improve ventilation [3]. Studies of EIT in adult patients with CF have shown that EIT offers advantages because it provides additional regional ventilation information compared to spirometry and highresolution CT [13,14]. In our previous study, we were able to demonstrate an association between spirometry and EIT in asthmatic children.…”

mentioning

confidence: 81%

Monitoring of lobectomy in cystic fibrosis with electrical impedance tomography – a new diagnostic tool

Lehmann

Tenbrock

Schrading

et al. 2014

Biomedical Engineering / Biomedizinische Technik

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Electrical impedance tomography (EIT) is a radiation-free technique generating cross-sectional images of the lung. EIT visualizes global and regional ventilation by illustrating the distribution of electrical bioimpedance. With an electrode belt around the patient's thorax, rotating injection-couples of a harmless alternating current allow voltage measurement of the remaining electrodes. This enables the reconstruction of a tomogram with highly dynamic changes within ventilation. We report on a female six-year-old patient with cystic fibrosis and complete destruction of the upper and middle lobe of the right lung. Lobectomy, a rare therapeutic option in patients with cystic fibrosis that needs to be considered in cases of severe localized destruction, was performed. We show a pre- and postoperative documentation of static (radiology) and dynamic investigation tools (spirometry) in correlation with EIT as a new non-invasive and radiation-free diagnostic tool for this patient group.

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mentioning

confidence: 81%

Monitoring of lobectomy in cystic fibrosis with electrical impedance tomography – a new diagnostic tool

Lehmann

Tenbrock

Schrading

et al. 2014

Biomedical Engineering / Biomedizinische Technik

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“…Currently, EIT is mainly used in the intensive care unit, where the regional information about lung ventilation is used to adjust ventilator parameters and thus prevent ventilator induced lung injuries [1]. Recently it has also been used in the examination of spontaneously breathing patients suffering from obstructive lung diseases such as chronic obstructive *Corresponding author: Benjamin Schullcke, Institute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany, E-mail: sben@hs-furtwangen.de Sabine Krueger-Ziolek, Bo Gong and Knut Moeller: Institute of Technical Medicine, Furtwangen University, VillingenSchwenningen, Germany lung disease (COPD) [2], cystic fibrosis (CF) [3] or asthma.…”

Section: Introductionmentioning

confidence: 99%

Effect of the number of electrodes on the reconstructed lung shape in electrical impedance tomography

Schullcke

Krueger-Ziolek

Gong

et al. 2016

Current Directions in Biomedical Engineering

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Electrical impedance tomography (EIT) is used to monitor the regional distribution of ventilation in a transversal plane of the thorax. In this manuscript we evaluate the impact of different quantities of electrodes used for current injection and voltage measurement on the reconstructed shape of the lungs. Results indicate that the shape of reconstructed impedance changes in the body depends on the number of electrodes. In this manuscript, we demonstrate that a higher number of electrodes do not necessarily increase the image quality. For the used stimulation pattern, utilizing neighboring electrodes for current injection and voltage measurement, we conclude that the shape of the lungs is best reconstructed if 16 electrodes are used.

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“…Electrical Impedance Tomography (EIT) is a radiationfree imaging method [1]. A commonly used imaging strategy is called time-difference reconstruction.…”

Section: Introductionmentioning

confidence: 99%

Regularization of EIT reconstruction based on multi-scales wavelet transforms

Gong

Schullcke

Krueger-Ziolek

et al. 2016

Current Directions in Biomedical Engineering

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Electrical Impedance Tomography (EIT) intends to obtain the conductivity distribution of a domain from the electrical boundary conditions. This is an ill-posed inverse problem usually solved on finite element meshes. Wavelet transforms are widely used for medical image reconstruction. However, because of the irregular form of the finite element meshes, the canonical wavelet transforms is impossible to perform on meshes. In this article, we present a framework that combines multi-scales wavelet transforms and finite element meshes by viewing meshes as undirected graphs and applying spectral graph wavelet transform on the meshes.

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Regional ventilation in cystic fibrosis measured by electrical impedance tomography

Abstract: Compared to the global parameters provided by spirometry, EIT is able to deliver both global and regional information to assess the airway obstruction in CF patients.

Cited by 75 publications

References 28 publications

Monitoring of lobectomy in cystic fibrosis with electrical impedance tomography – a new diagnostic tool

Monitoring of lobectomy in cystic fibrosis with electrical impedance tomography – a new diagnostic tool

Effect of the number of electrodes on the reconstructed lung shape in electrical impedance tomography

Regularization of EIT reconstruction based on multi-scales wavelet transforms

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