Regional variations of symptoms of the chronic venous disease among primary health care patients in Poland

Ziaja, Damian; Sznapka, Mariola; Grzela, Joanna; Kostecki, Jacek; Biolik, Grzegorz; Pawlicki, Krzysztof; Ziaja, Krzysztof; Chudek, Jerzy; Maruszyński, Marek; Molski, Aleksander; Sieroń, Aleksander

doi:10.5603/aa.2015.0007

Cited by 4 publications

(3 citation statements)

References 4 publications

(14 reference statements)

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“…De acordo com a Scottish Intercollegiate Guidelines Network, as Úlceras Venosas também denominada úlcera de estase ou varicosa, são as lesões mais graves da Síndrome da Insuficiência Venosa Crônica dos membros inferiores. A Úlcera Venosa é um problema de saúde pública por demandar cuidados contínuos, gerar altos custos para os sistemas de saúde e restringir a capacidade funcional do indivíduo interferindo de forma negativa na qualidade de vida dos pacientes (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13) .…”

Section: Introductionunclassified

Qualidade de vida e autoestima de pacientes com úlcera venosa

Filho¹,

Blanes²,

Castro³

et al. 2021

Nursing (São Paulo)

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Objetivo: Avaliar a qualidade de vida e autoestima de pacientes com úlcera venosa. Método: Estudo primário, exploratório, observacional, transversal e descritivo realizado com 75 pacientes atendidos na Atenção Primária de Conselheiro Lafaiete-MG no período de dezembro de 2018 a maio de 2019 com a aplicação da Escala de autoestima de Rosenberg e o questionário de qualidade de vida SF-36. Resultados: O gênero feminino foi mais prevalente (60%), idade média de 68,9 anos e predomínio de doenças crônico-degenerativas. O levantamento das médias da Escala de Autoestima de Rosenberg teve maiores pontuações foram relacionadas ao gênero feminino, raça branca, aposentados, tabagistas, etilistas, com HAS e DM. Conclusão: A presença de úlcera venosa interferiu negativamente na autoestima de ambos os gêneros, entretanto o gênero masculino apresenta melhores escores quando comparados ao gênero feminino.

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Section: Introductionunclassified

Qualidade de vida e autoestima de pacientes com úlcera venosa

Filho¹,

Blanes²,

Castro³

et al. 2021

Nursing (São Paulo)

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“…As previously shown limb heaviness (72.9%), ankle swelling (68.4%), and nighttime leg cramps (58.6%) are the most frequent CVD signs reported by patients, with a difficultto-explain significant territorial diversity in the prevalence at least across Poland [23]. It seems that the prevalence of symptoms could be affected by the judgment of the cause of symptoms in patients with multimorbidity, which may be dependent on some regional differences in pre-and postgraduate training of physicians.…”

Section: Discussionmentioning

confidence: 83%

Assessment of the Tolerance of Dobenox Forte® in Patients with Chronic Venous Disease

Chudek,

Almgren-Rachtan,

Pastuszka

et al. 2024

Life

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This prospective, observational, multicenter study assessed the tolerance of Dobenox Forte®, the first approved over-the-counter product containing calcium dobesilate, in 1795 outpatients with chronic venous disease (CVD) in daily clinical practice. In addition, the effectiveness (decrease in circumferences of a more affected limb at the ankle and middle part of the calf, and changes in the severity of CVD signs) was assessed. No adverse events related to use of the preparation were reported in a period of 64 ± 20 days. Dobenox Forte® use was associated with a reduction in calf circumference by 13.1 mm (95%CI: 12.2–14.1) and in ankle circumference by 9.7 mm (95%CI: 9.2–11.0) in patients reporting swelling of the lower legs (60.0% of the cohort). A reduction in calf and ankle circumference by at least 1 cm was achieved in 34.9% and 24.9% of patients, respectively. The percentages of patients reporting moderate to very severe lower limb heaviness decreased from 96.6% to 56.0%, calf cramps decreased from 91.0% to 41.0%, calf pain decreased from 89.2% to 43.7%, swelling decreased from 86.1% to 38.8%, and burning sensation that worsens when standing decreased from 79.0% to 33.7%. The medicinal product Dobenox Forte® is well tolerated by patients and seems to effectively reduce the symptoms of CVD.

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“…In a large epidemiological study conducted in 2003 in Poland, signs of CVD were reported in 47% of all women and 37% of all men [12]. In a subsequent study conducted in Poland involving 13.393 participants, initial symptoms of CVD were observed in 56.1% of all subjects [13]. The adverse socio-economic impact of CVD Current Issues in Pharmacy and Medical Sciences is particularly determined by the occurrence of venous ulcers, which significantly reduces the daily activity of patients and their quality of life [1,14].…”

Section: Microrna Expression Biomarkers Of Chronic Venous Diseasementioning

confidence: 99%

MicroRNA expression biomarkers of chronic venous disease

Zalewski

Chmiel

2022

Current Issues in Pharmacy and Medical Sciences

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Chronic venous disease (CVD) is a common disease caused by hemodynamic disorders of the venous circulation in the lower extremities. The clinical image of this disease is complex and includes such signs as telangiectases, varicose veins, leg edema and skin changes, usually accompanied with ache, pain, tightness, heaviness, swelling and muscle cramps of legs. Venous ulcers develop in the advanced stages of the disease and lead to significant impairment of patient abilities and reduction of the quality of life. CVD is diagnosed based on physical and image examinations, and main treatment options include compression therapy, invasive treatments like endovenous ablation and foam sclerotherapy, as well as pharmacotherapy. Currently, there is no biochemical and molecular biomarkers utilized in diagnosis or treatment of CVD. With regard to this situation, one of the most investigated fields for identification of disease biomarkers is microRNA (miRNA). These constitute a pool of small, non-coding RNAs that play crucial roles in maintaining cellular homeostasis through posttranscriptional regulation of genes expression. Dysregulations of miRNA expression profiles have been found in patients with various diseases, and this situation provides information about potential miRNA signatures involved in pathophysiology. In this review, the studies focused on investigations of miRNA expression patterns in patients with CVD were collected. The performed literature analysis provides contemporary knowledge in the field of miRNA-dependent mechanisms involved in the etiopathogenesis of CVD and shows gaps that need to be filled in further studies.

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Regional variations of symptoms of the chronic venous disease among primary health care patients in Poland

Abstract: The presented results were collected in the context of the PHLEBOS-2 research (multi-centre epidemiological study of patients suffering from chronic venous disease) carried out under the scientific grant of LEKAM Company with limited liability in the years 2011-2012. Abstract

Cited by 4 publications

References 4 publications

Qualidade de vida e autoestima de pacientes com úlcera venosa

Qualidade de vida e autoestima de pacientes com úlcera venosa

Assessment of the Tolerance of Dobenox Forte® in Patients with Chronic Venous Disease

MicroRNA expression biomarkers of chronic venous disease

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