Regional variability in changes in the incidence of hip fracture in the Spanish population (2000–2012)

Etxebarría-Foronda, I.; Arrospide, Arantzazu; Soto-Gordoa, Myriam; Caeiro, J.R.; Abecia, Luis Carlos; Mar, Javier

doi:10.1007/s00198-014-3015-8

Cited by 32 publications

(11 citation statements)

References 40 publications

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“…The crude incidence rate changed from 259.24 to 664.79 in 1997 to 325.30 and 766.37 in 2010, for men and women respectively (the study group consisted of patients 65+ years) [ 21 ]. The increasing trend of number of hip fractures was also confirmed by Foronda who analysed data in different regions of Spain [ 22 ]. In general, the number of hip fractures increases, but in some countries, the trend of incidence rate is decreasing [ 7 , 10 ].…”

Section: Discussionmentioning

confidence: 56%

The 13-year observation of hip fracture in Poland—worrying trend and prognosis for the future

et al. 2017

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IntroductionHip fractures are often considered to be one of the most common osteoporotic fractures. In our previous study, we noted the increasing trend in the total number of hip fractures as well as crude and standardized rates, for both women and men. This observation enabled us to delve deeper into the study of osteoporotic fractures.MethodsHospital records between 1.01.2002 and 31.12.2014 with ICD-10 codes S72.0. S72.1 and S72.2 (femoral neck. intertrochanteric, subtrochanteric, and inter and subtrochanteric fracture) were analysed. All fractures occurred in citizens who lived in the district Tarnowskie Góry and the city of Piekary Śląskie aged 50 years and more.Results1507 fragility hip fractures (400 in men, and 1107 in women) were registered. The rates increase in both sexes was still observed. The tendency to sustain fractures was lower in female (29.3%) than in the male population (63.6%). We observed a lower increase in urban (35.8%) population when compared to rural (40.8%) population. Incidence rate ratios for female gender were 1.89 (95% CI 1.65–2.18). The rates in 2014 were as follows: crude rate of 216.2 (men 140.9; women 276.5) and standardized 183.9 (131.6 and 219.4, respectively). This observation allowed as to project a total crude rate of 467.2 (men 329.6; women 584.7) for the year 2050.ConclusionsThe number of osteoporotic hip fractures in Polish men and women is still relatively low, but the epidemiological situation is getting worse. The over 13 years of follow-up demonstrated that the trend to increase in total number of hip fractures for men and women is still observed. This prognosis is of a major concern.

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Section: Discussionmentioning

confidence: 56%

The 13-year observation of hip fracture in Poland—worrying trend and prognosis for the future

et al. 2017

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“…The strongest inequalities were observed in women between 65 and 79 years of age and increased during the BJD: while HF incidence persistently decreases in the affluent regions, the decrease in the medium regions was only for a short period of 3 years and, in the deprived regions, there was no decreasing period; besides, there are increasing trends starting first in 2006 in the deprived regions and later, in 2007, in the medium regions. Our results seem to show that HF reduction from 2000 to 2010 have mainly reached a restricted group: women aged 65–79 years in the affluent regions, the preferential target population for medication and treatment against osteoporosis and HF,31 32 while sustainable reduction seems to have failed for all the other men and women. All stable or increasing trends in 2000 (for all age groups and regional SES among women) turned to accentuate decreasing trends around 2002/2003, although such turning points were rarely observed for men.…”

Section: Discussionmentioning

confidence: 63%

Marked socioeconomic inequalities in hip fracture incidence rates during the Bone and Joint Decade (2000–2010) in Portugal: age and sex temporal trends in a population based study

Oliveira

Alves

Pina

2016

J Epidemiol Community Health

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Background Socioeconomic factors may influence changes in hip fracture (HF) incidence over time. We analysed HF temporal trends during the Bone and Joint Decade in Portugal (BJD-Portugal), 2000-2010, by regional socioeconomic status (SES), sex and age. Methods We selected registers of patients aged 50+ years with HF (International Classification of Diseases, V.9-Clinical Modification, ICD9-CM) caused by traumas of low/moderate energy, from the National Hospital Discharge Database. Annual time series of age-specific incidence rates were calculated by sex and regional SES (deprived, medium, affluent). Generalised additive models were fitted to identify shape/turning points in temporal trends. Results We selected 96 905 HF (77.3% in women). Women were older than men at admission (81.2±8.5 vs 78.2±10.1 years-old, p<0.001). For women 65-79 years, a continuously decreasing trend (1.7%/year) only in affluent and increasing trends (3.3-3.4%/year) after 2006/2007 in medium and deprived was observed. For men, trends were stable or increased in almost all age/SES groups (only two decreasing periods). For the oldest women, all SES present similar trends: turning points around 2003 (initiating decreasing periods: 1.8-2.9%/year) and around 2007 (initiating increasing periods: 3.7-3.3%/year). Conclusions There were SES-sex-age inequalities in temporal trends during BJD-Portugal: marked SES inequalities among women aged 65-79 years (a persistent, decreasing trend only in the affluent) vanished among the oldest women; the same was not observed in men, for them, there were almost no declining periods; women aged ≥80 years, presented increasing trends around 2007, as in most deprived/age/ sex groups. Despite some successful periods of decreasing trends, incidence rates did not improve overall in almost all age groups and both sexes.

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“…First, although our cohort includes all patients after a hip fracture from Valencia, a region covering a population of 5 million inhabitants, this population represents approximately 11% of the overall Spanish population. Thus, results should be extrapolated with caution, especially given that studies have shown a considerable variability in hip fracture rates and osteoporotic treatment between different regions, even within the same country 21 , 22 . Second, we calculate secondary non-adherence with dispensing but no prescription data, so we cannot discern whether treatment interruption is instructed by clinicians or is due to patient’s non-adherence.…”

Section: Discussionmentioning

confidence: 99%

“…In Spain, the annual incidence of hip fracture is estimated at 72 and 28 per 10,000 women and men respectively, totalling roughly 40,000 hip fractures/year 6 . Moreover, the age and sex standardised rate of hip fracture per 10,000 inhabitants has remained relatively stable in the period 2000–2012 7 despite significant increments in osteoporotic medication prescription in the Spanish National Health System.…”

Section: Introductionmentioning

confidence: 99%

Primary and secondary non-adherence to osteoporotic medications after hip fracture in Spain. The PREV2FO population-based retrospective cohort study

García‐Sempere

Hurtado

Sanfélix-Genovés

et al. 2017

Sci Rep

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Osteoporotic medication after hip fracture is widely recommended by clinical practice guidelines, and medication adherence is essential to meet clinical trial risk reduction figures in the real world. We assessed primary and secondary non-adherence to osteoporosis medications in patients discharged following a hip fracture and identified factors associated with secondary non-adherence. From a population-based retrospective cohort of 19,405 patients aged 65 years and over discharged from a hip fracture in the region of Valencia (Spain) from January 1, 2008 and June 30, 2012, we followed, over a minimum of 365 days, 4,856 patients with at least one osteoporotic medication prescribed within the first six months after discharge. Less than one third of the patients discharged alive after a hip fracture received osteoporotic treatment. Primary non-adherence among naïve patients was low. However, long-term secondary adherence measured by Proportion of Days Covered with medication (PDC) and persistence was largely suboptimal, with naïve users having worse results than experienced patients. Secondary non-adherence was associated with primary non-adherence and age, dementia or sedative treatments for naïve users and with being male, being older than 85 and having dementia for experienced users. Three quarters of naïve users and two thirds of experienced users had interrupted treatment at 48 months.

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Regional variability in changes in the incidence of hip fracture in the Spanish population (2000–2012)

Cited by 32 publications

References 40 publications

The 13-year observation of hip fracture in Poland—worrying trend and prognosis for the future

The 13-year observation of hip fracture in Poland—worrying trend and prognosis for the future

Marked socioeconomic inequalities in hip fracture incidence rates during the Bone and Joint Decade (2000–2010) in Portugal: age and sex temporal trends in a population based study

Primary and secondary non-adherence to osteoporotic medications after hip fracture in Spain. The PREV2FO population-based retrospective cohort study

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