1990
DOI: 10.1016/s0002-8703(05)80011-0
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Regional myocardial blood flow with areperfusion catheter and an autoperfusion balloon catheter during total coronary occlusion

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Cited by 17 publications
(5 citation statements)
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“…It was developed about a decade ago (30,31) to increase safety of PTCA procedures in high-risk patients and to allow for prolonged inflation times in patients with rigid stenosis. With such perfused catheters, coronary ischemic times during PTCA have been prolonged from 30-60 seconds up to 10 minutes in humans (34,36), up to 30 minutes in pigs (35), and 90 minutes in dogs (38) before the occurrence of ischemic events. Improvements in material design coupled with the availability of intravascular stents obviate the need for prolonged balloon inflation times during PTCA in most patients today.…”
Section: Discussionmentioning
confidence: 99%
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“…It was developed about a decade ago (30,31) to increase safety of PTCA procedures in high-risk patients and to allow for prolonged inflation times in patients with rigid stenosis. With such perfused catheters, coronary ischemic times during PTCA have been prolonged from 30-60 seconds up to 10 minutes in humans (34,36), up to 30 minutes in pigs (35), and 90 minutes in dogs (38) before the occurrence of ischemic events. Improvements in material design coupled with the availability of intravascular stents obviate the need for prolonged balloon inflation times during PTCA in most patients today.…”
Section: Discussionmentioning
confidence: 99%
“…In this context, the occurrence of thrombosis within the sideholes or the guidewire channel during prolonged inflations must be carefully monitored (34). Heparinization of the animal and frequent flushing of the catheter with heparin (500 IU/mL saline solution) should thus be assured (34,38). At the time of catheter withdrawal from the left internal carotid artery, no thrombus was observed in any of the sideholes of the catheter or lumen.…”
Section: Discussionmentioning
confidence: 99%
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“…Advances in catheter-based reperfusion technology have yielded a variety of devices that can be rapidly and safely deployed. In animal models, the 4.3F autoperfusion catheter allows regional perfusion rates of 0.63 mUmin/g tissue [8]. Other animal studies suggest they are effective in reducing ischemic damage to hearts under conditions of experimental vessel occlusion.…”
Section: Discussionmentioning
confidence: 99%
“…The in vitro flow measured in rigid glass tubes can only approximate the flow present in diseased arteries [15]. In the in vivo setting, lower net flow rates would be expected due to the phasic nature of myocardial perfusion occurring primarily during diastole.…”
Section: Limitationsmentioning
confidence: 99%