Regional left ventricular performance in the year following myocardial infarction

Post-Conditioning Reduces Infarct Size and Edema in Patients With ST-Segment Elevation Myocardial Infarction

“…Left ventricular (LV) and coronary angiography was performed using standard techniques just before revascularization. The size of the area at risk was estimated for each patient by measuring the circumferential extent of abnormally contracting segments (ACS) according to the method of Feild et al (16) and Lapeyre et al (17), as performed in previous randomized trials (11,18). Briefly, the length of the end-diastolic ventricular endocardial perimeter (circumference) and the length of the ACS of the enddiastolic perimeter were determined by computerized planimetry (Image J 1.38ϫ software).…”

Myocardial Protection Via the Coronary Sinus Long-Term Effects of Intermittent Coronary Sinus Occlusion as an Adjunct to Reperfusion in Acute Myocardial Infarction

“…Enzymatic activity of creatine kinase (CK) was measured, as described elsewhere, and total CK release was determined using the integrated appearance function curve with the individual disappearance constant, as described elsewhere. 5,12,13 Abnormality in wall motion was calculated by abnormally contracting segments, 14 global ejection fraction and regional ejection fraction, using the area method, 15 from the left ventriculogram at 30 days after onset of symptoms (ie, before hospital discharge). 5 To assess myocardial infarct size, 32 projections of single photoemission computerized The volume of defects was weighted for the average value of counts in the defect area, and this was defined as the extent of damaged myocardium in the total left ventricle or 'defect severity', as described elsewhere.…”

Postconditioning in man

“…In both groups, when full (TIMI > 2) reflow was not obtained, the patient was excluded from analysis (because infarct size assessment by CK release becomes invalid). A LV angiogram was obtained before re-opening of the occluded coronary artery in order to estimate the size of the area at risk, according to the method of Feild et al [10]. Area under the curve of CK release over the first 72 h of reperfusion was used as a Fig.…”