Regional differences in heart failure risk in the United Kingdom are partially explained by biological aging
Jason Y. Y. Wong,
Batel Blechter,
Erik J. Rodriquez
et al.
Abstract:BackgroundHeart failure (HF) risk is greater in rural versus urban regions in the United States (US), potentially due to differences in healthcare coverage and access. Whether this excess risk applies to countries with universal healthcare is unclear and the underlying biological mechanisms are unknown. In the prospective United Kingdom (UK) Biobank, we investigated urban–rural regional differences in HF risk and the mechanistic role of biological aging.MethodsMultivariable Cox regression was used to estimate … Show more
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