Regional diastolic function in ischaemic heart disease using pulsed wave Doppler tissue imaging

Ma, García-Fernández; Azevedo, J; Moreno, Mar; Bermejo, Javier; Pérez‐Castellano, Nicasio; Puerta, Pablo; Desco, Manuel; Antoranz, Carlos; Serrano, José Antonio; Garcı́a, Eulogio; Delcán, Juan L.

doi:10.1053/euhj.1998.1278

Cited by 179 publications

(97 citation statements)

References 27 publications

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“…Specific cardiac diseases known from TDI measurements that may be suitable for TPM investigations include ischemic cardiomyopathy (2), hypertrophic cardiomyopathy (3), heart trans- plant recipients (4), LV hypertrophy (5), and differentiating constrictive pericarditis from restrictive cardiomyopathy (6). It has been suggested that regional relaxation dysfunction induces a prolongation of the IVR in ischemic cardiomyopathy (2).…”

Section: Discussionmentioning

confidence: 99%

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Detailed analysis of myocardial motion in volunteers and patients using high‐temporal‐resolution MR tissue phase mapping

Jung

Föll

Böttler

et al. 2006

Magnetic Resonance Imaging

115

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Purpose: To detect and investigate details in left ventricular (LV) motion patterns with a temporal resolution comparable to that of echocardiography. Material and Methods:To assess global and regional myocardial motion in high temporal detail, respiratory-gated MR phase-contrast measurements with three-directional velocity encoding (venc) were performed in 12 healthy volunteers and two patients with LV hypertrophy in basal, midventricular, and apical locations of the LV with a temporal resolution of 13.8 msec. Results:The volunteer data revealed details in LV motion patterns that were known only from echocardiography. For all volunteers, characteristic myocardial motion patterns, such as triphasic global diastolic expansion, could be detected with high accuracy. One volunteer underwent an additional echocardiographic measurement in order to corroborate the complex motion features as measured by MRI. Patient examinations revealed substantial changes in diastolic function compared to motion patterns in healthy volunteers. Conclusion:The proposed high-temporal-resolution velocitymapping technique provides previously undetectable information on LV performance, and is highly promising for the detection of local and global motion abnormalities in patients with disturbed LV performance, such as diastolic dysfunction.

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Section: Discussionmentioning

confidence: 99%

“…Diastolic dysfunction accounts for up to half of all heart-failure cases (1). Many experimental studies suggest that regional myocardial relaxation disorders are related to specific cardiac diseases, such as ischemic or hypertrophic cardiomyopathy and LV hypertrophy (2)(3)(4)(5)(6).…”

mentioning

confidence: 99%

Detailed analysis of myocardial motion in volunteers and patients using high‐temporal‐resolution MR tissue phase mapping

Jung

Föll

Böttler

et al. 2006

Magnetic Resonance Imaging

115

View full text Add to dashboard Cite

show abstract

“…[3][4][5][6][7][8][9][10] It is frequently observed in patients with CAD presenting with LV asynergy. [23][24][25] Earlier studies have demonstrated the presence of abnormal diastolic function in patients with CAD without evidence of systolic wall motion abnormalities by radionuclide angiography or digitized cineangiography. [26][27][28] Kondo et al have also demonstrated that delayed outward LV wall motion in the isovolumic relaxation phase by digital subtraction high-frame-rate echocardiography was indicative of CAD.…”

Section: Discussionmentioning

confidence: 99%

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

Onishi

Uematsu

Nanto

et al. 2009

Circ J

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Background Post-systolic shortening (PSS) is a sensitive indicator of myocardial ischemia. Methods and ResultsWe have developed a tissue Doppler imaging technique that portrays PSS, and whether PSS correlates with coronary artery disease (CAD) was investigated in 186 patients presenting with chest pain and normal echocardiograms. Delays of the displacement peaks from end-systole were calculated in the apical views and displayed from green (0 ms) to red (≥100 ms): detection of diastolic abnormality by dyssynchrony imaging (DADI). CAD was judged positive by DADI when the left ventricular segments were color-coded red. Patients subsequently underwent thallium-201 myocardial perfusion single-photon emission computed tomography (n=150), coronary angiography (CAG, n=74), or both (n=37). CAD(-) was defined as negative scintigraphy test and/or no significant coronary artery stenosis by CAG. In 43 patients (23%), CAD(+) was confirmed by CAG as >75% diameter stenosis. DADI predicted CAD with sensitivity of 60%, specificity of 75%, predictive accuracy of 72%, positive predictive value of 42%, and negative predictive value of 86%. Among 74 patients who underwent CAG, sensitivity was best for the left anterior descending artery. Conclusions DADI detected the regional diastolic abnormality, which correlated with the presence of CAD in patients presenting with visibly normal wall motion. (Circ J 2009; 73: 125 -131)

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“…The ventricular diastolic filling pattern (E and A waves) is frequently used to represent the ventricular relaxation, which is affected by several factors such as internal loading forces, wall stress, and myocardial contraction. 17 There are many clinical reports of the E-wave velocity and E/A ratio being decreased in patients with ischemic myocardial injury, 18 and of the E-wave velocity being faster for young adults than for older adults (as well as E/A ratio usually also decreasing with age), which may be attributed to reductions of the ventricular compliance and contraction. 25 However, the E-wave velocity and E/A ratio of the zebrafish were increased after partial amputation of the ventricle, which means that myocardial injury appears to promote ventricular diastolic filling.…”

Section: Figmentioning

confidence: 99%

“…Duplex echocardiography including color M-mode imaging (CMI) and pulsed-wave Doppler sonography has been extensively used for diagnosing cardiovascular diseases in human 17,18 and in studies of small animals such as rats and mice. 19,20 Tissue Doppler imaging (TDI) is a relatively new echocardiography technique proposed for the clinical evaluation of the cardiac functions of the human heart.…”

Section: Introductionmentioning

confidence: 99%

High-Resolution Tissue Doppler Imaging of the Zebrafish Heart During Its Regeneration

Huang

Shih

2015

Zebrafish

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The human heart cannot regenerate after injury, whereas the adult zebrafish can fully regenerate its heart even after 20% of the ventricle is amputated. Many studies have begun to reveal the cellular and molecular mechanisms underlying this regenerative process, which have exciting implications for human cardiac diseases. However, the dynamic functions of the zebrafish heart during regeneration are not yet understood. This study established a high-resolution echocardiography for tissue Doppler imaging (TDI) of the zebrafish heart to explore the cardiac functions during different regeneration phases. Experiments were performed on AB-line adult zebrafish (n = 40) in which 15% of the ventricle was surgically removed. An 80-MHz ultrasound TDI based on color M-mode imaging technology was employed. The cardiac flow velocities and patterns from both the ventricular chamber and myocardium were measured at different regeneration phases relative to the day of amputation. The peak velocities of early diastolic inflow, early diastolic myocardial motion, late diastolic myocardial motion, early diastolic deceleration slope, and heart rate were increased at 3 days after the myocardium amputation, but these parameters gradually returned to close to their baseline values for the normal heart at 7 days after amputation. The peak velocities of late diastolic inflow, ventricular systolic outflow, and systolic myocardial motion did not significantly differ during the heart regeneration.

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Regional diastolic function in ischaemic heart disease using pulsed wave Doppler tissue imaging

Cited by 179 publications

References 27 publications

Detailed analysis of myocardial motion in volunteers and patients using high‐temporal‐resolution MR tissue phase mapping

Detailed analysis of myocardial motion in volunteers and patients using high‐temporal‐resolution MR tissue phase mapping

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

High-Resolution Tissue Doppler Imaging of the Zebrafish Heart During Its Regeneration

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