Regional Cerebral Blood Flow in Patients with Alcohol-Related Dementia: A Spect Study

Abstract

The purpose of this study was to investigate regional cerebral blood flow (rCBF) changes using 1110 MBq of Tc-99m ECD SPECT in alcohol-related dementia (ARD) patients. Twenty-five patients with ARD and 22 healthy control subjects were included in the study. Mini-Mental Status Examination was applied to the patients and controls. The ARD patients showed drastically reduced rCBF in the frontal cortices, basal ganglia, and thalami. The results indicate that ARD is associated with hypoperfusion in both cortical and subcortical regions. These findings support previous studies suggesting the association with both cortical and subcortical neuropathology in ARD patients.

Alcohol-Related Dementia and Neurocognitive Impairment: A Review Study

“…Though smaller in their sample size, few studies have proposed that the clinical profile of ARD reflects both cortical and subcortical pathology (52). Recent single photon emission CT study supported above findings by reporting hypometabolism in the frontal cortices, thalami and basal ganglia in ARD cases (13). …”

“…He expected this classification would bring more clarity and stimulate further research in this area (12). Even till now, only a few studies have adopted these criteria and they still need research for being conclusive (13-15). …”

Brain Areas Involved in Acupuncture Needling Sensation of de qi: A single-photon emission computed tomography (SPECT) study

“…Results All six subjects in the verum acupuncture at true acupuncture point group experienced de qi sensation; in contrast, all six subjects in the sham acupuncture at the sham point group responded with nothing other than non-sensation. Compared to the scan results from subjects who experienced non-sensation, SPECT scans from subjects with de qi sensation demonstrated significant activated points mainly located in brodmann areas 6,8,19,21,28, 33, 35, 37, 47, the parahippocampal gyrus, lentiform nucleus, claustrum and red nucleus; deactivated points were seen in brodmann areas 9 and 25. Conclusions Verum acupuncture at true acupuncture points is more likely to elicit de qi sensation.…”

“…Subjects with de qi sensation demonstrated that significant activated points are mainly located in Brodmann areas 6,8,19,21,28,33,35,37,47, parahippocampal gyrus, lentiform nucleus, claustrum and red nucleus, and deactivated points were shown in Brodmann areas 9 and 25. into de qi group, or use of different acupuncture points, or they may have arisen from differences in the statistical methodology and level of thresholding used.…”

Brain perfusion single photon emission computed tomography in major psychiatric disorders: From basics to clinical practice

“…Brain SPECT, has shown disseminated CBF defects in abusers of cocaine, crack, heroin and alcohol. [707172737475] [Figures 7 and 8]. Disappearance or improvement of the defects after a period of abstinence has been described, suggesting that arterial spasms may cause the defects.…”