Regional and neuraxial anaesthesia techniques for spinal surgery: a scoping review

Eochagáin, Aisling Ní; Singleton, Barry N; Moorthy, Aneurin; Buggy, Donal J.

doi:10.1016/j.bja.2022.05.028

Cited by 8 publications

(5 citation statements)

References 83 publications

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“…Regional anaesthesia contributes to an important component of the multimodal analgesia strategy by reducing postoperative pain intensity and opioid consumption. [1][2][3][4] With advancements in ultrasound techniques, various peripheral nerve blocks have been widely used for many surgery types. Ultrasound-guided quadratus lumborum block, first reported in 2007, is effective in providing postoperative analgesia for abdominal surgeries by spreading the local anaesthetic across the quadratus lumborum muscle to block the intermuscular nerves.…”

Section: Introductionmentioning

confidence: 99%

Comparison of the effects of ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in abdominal surgeries: a protocol for systematic review and meta-analysis

Zhang,

Wang

et al. 2024

BMJ Open

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IntroductionUltrasound-guided quadratus lumborum block and erector spinae plane block are widely used for postoperative analgesia in adult patients undergoing abdominal surgeries. This protocol aims to compare the analgesic effects between ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in abdominal surgeries.Methods and analysisFour databases, including PubMed, EMBASE, Web of Science and the Cochrane Central Register of Controlled Trials (CENTRAL), will be searched. Randomised controlled trials that compared the analgesic effects between ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in adult patients will be identified. The primary outcomes are time to the first analgesic request and postoperative analgesic consumption over 24 hours. Secondary outcomes will include postoperative pain scores and the incidence of side effects. RevMan V.5.3 software will be used for data processing and statistical analysis. The Grading of Recommendation, Assessment, Development and Evaluation approach will be used to assess the evidence quality of outcomes.Ethics and disseminationEthical approval is not required for this study. Results of this present study will be submitted to a peer-reviewed journal.PROSPERO registration numberCRD42023445802.

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Section: Introductionmentioning

confidence: 99%

Comparison of the effects of ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in abdominal surgeries: a protocol for systematic review and meta-analysis

Zhang,

Wang

et al. 2024

BMJ Open

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“…Regional block is a common method for clinical anesthesia and treatment of acute and chronic pain. [1][2][3] Regional block has the advantages of rapid onset, accurate clinical effect and small systemic impact. However, nerve injury caused by regional block is often reported.…”

Section: Introductionmentioning

confidence: 99%

Establishment of an animal model of sciatic nerve injury induced by local anesthetics

Liang

et al. 2023

Hum Exp Toxicol

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Peripheral neurotoxicity injury caused by local anesthetics is a common complication of clinical anesthesia. The study of its mechanism is helpful to prevent and treat the neurotoxic injury of local anesthetics. Previous studies on peripheral neurotoxicity injury caused by local anesthetics have mainly focused on in vitro cell experiments. Due to the lack of an animal model of peripheral neurotoxicity damage caused by local anesthetics, there are few in vivo experimental studies regarding this topic. Herein, 1% ropivacaine hydrochloride was injected into the sciatic nerve by direct incision and exposure of the sciatic nerve to create a local anesthetic neurotoxic injury model. The results showed that 1% ropivacaine hydrochloride could reduce the lower limb motor score and mechanical paw withdrawal threshold in mice 48 hours after injection. Pathological sections showed that 48 hours after treatment with 1% ropivacaine hydrochloride, the sciatic nerve showed increased axonal edema and degeneration, edema between nerve fiber bundles, increased degeneration of axon and myelin sheath vacuoles, edema of nerve bundle membrane and local degeneration and necrosis, and a large number of inflammatory cells around the nerve adventitia were soaked. The above results show that under open vision, 1% ropivacaine hydrochloride can cause injury to the sciatic nerve after 48 h of treatment, which can simulate the neurotoxic damage of local anesthetics. This animal model provides a research tool for studying the mechanism of neurotoxic injury caused by local anesthetics.

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“…Peripheral nerve blocks (PNBs) are widely used to provide perioperative analgesia for various types of surgeries 1–3. In addition to pain relief, PNB can also reduce the consumption of general anaesthetics and/or opioids, decrease the incidence of postoperative complications and improve the recovery quality 4–6. Currently, ropivacaine is the most commonly used local anaesthetic for PNB due to its lower toxicity in the central nervous system and heart 7 8.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3] In addition to pain relief, PNB can also reduce the consumption of general anaesthetics and/or opioids, decrease the incidence of postoperative complications and improve the recovery quality. [4][5][6] Currently, ropivacaine is the most commonly used local anaesthetic for PNB due to its lower toxicity in the central nervous system and heart. 7 8 The concentrations of ropivacaine used for PNB are various, and the efficacy and safety of different concentrations of ropivacaine have been compared in several RCTs, [9][10][11][12][13][14] but the results were inconsistent.…”

Section: Introductionmentioning

confidence: 99%

Optimal concentration of ropivacaine for peripheral nerve blocks in adult patients: a protocol for systematic review and meta-analysis

Li,

Pan,

et al. 2023

BMJ Open

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IntroductionRopivacaine is the most widely used local anaesthetic for peripheral nerve blocks (PNBs). The effects of various concentrations of ropivacaine in PNB have been investigated and compared by many randomised controlled trials (RCTs). This protocol aims to identify the optimal concentration of ropivacaine for PNB in adult patients.Methods and analysisPubMed, EMBASE, the Cochrane library and Web of Science will be searched from their inception to 10 July 2023. RCTs that compare the analgesic effects of different concentrations of ropivacaine for PNB will be included. Retrospective studies, meta-analyses, reviews, case reports, letters, conference abstracts and paediatric studies will be excluded. The duration of analgesia will be named as the primary outcome. Secondary outcomes will include the onset time of motor and sensory blockade, postoperative pain scores, analgesic requirements over 24 hours and the incidence of adverse effects. The study selection, data extraction and quality assessment will be performed by two independent reviewers. Data processing and analysis will be performed by RevMan 5.4. The quality of the evidence will be assessed by the Grading of Recommendations Assessment, Development and Evaluation approach.Ethics and disseminationEthical approval is not applicable. The results of this study will be submitted to peer-reviewed journals.PROSPERO registration numberCRD42023406362.

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Regional and neuraxial anaesthesia techniques for spinal surgery: a scoping review

Cited by 8 publications

References 83 publications

Comparison of the effects of ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in abdominal surgeries: a protocol for systematic review and meta-analysis

Comparison of the effects of ultrasound-guided quadratus lumborum block and erector spinae plane block on postoperative pain in abdominal surgeries: a protocol for systematic review and meta-analysis

Establishment of an animal model of sciatic nerve injury induced by local anesthetics

Optimal concentration of ropivacaine for peripheral nerve blocks in adult patients: a protocol for systematic review and meta-analysis

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