Regio- and Stereoselective 1,3-Dipolar Cycloaddition of C-Aryl-N-phenylnitrones over (E)-Arylidene-(2H)-indan-1-ones: Synthesis of Highly Substituted Novel Spiro-isoxazolidines

Monnier-Jobé, Karin; Wannassi, Nadia; Rammah, Mohamed M.; Boudriga, Sarra; Ciamala, Kabula; Knorr, M.; Rousselin, Yoann; Kubicki, Marek M.; Enescu, Mironel

doi:10.3987/com-10-12022

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ChemInform Abstract: Regio‐ and Stereoselective 1,3‐Dipolar Cycloaddition of C‐Aryl‐N‐phenylnitrones over (E)‐Arylidene‐(2H)‐indan‐1‐ones: Synthesis of Highly Substituted Novel Spiroisoxazolidines.

Rammah

2011

ChemInform

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Regio-and Stereoselective 1,3-Dipolar Cycloaddition of C-Aryl-N-phenylnitrones over (E)-Arylidene-(2H)-indan-1-ones: Synthesis of Highly Substituted NovelSpiroisoxazolidines. -The regiochemistry of the reaction seems to be independent of the electronic nature of substituents in both dipolarophile and dipole and the diastereoselectivity is rationalized as combination of electronic and steric interactions. -(RAMMAH*, M. E. B.; et al.; Heterocycles 81 (2010) 12, 2749-2762, http://dx.doi.org/10.3987/com-10-12022 ; Dep. Chim., Fac. Sci., 5000 Monastir, Tunisia; Eng.) -H. Haber

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