2018
DOI: 10.21873/anticanres.12186
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Regimens of Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis from Colorectal Cancer

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Cited by 17 publications
(21 citation statements)
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“…PC is commonly managed by the surgical cytoreduction of macroscopic lesions 23 which can be accompanied with intraperitoneal chemotherapy 19. The effectiveness of surgery mainly relies on the complete removal of tumor tissue, which in turn is directly correlated with the ability to visualize microscopic lesions.…”
Section: Discussionmentioning
confidence: 99%
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“…PC is commonly managed by the surgical cytoreduction of macroscopic lesions 23 which can be accompanied with intraperitoneal chemotherapy 19. The effectiveness of surgery mainly relies on the complete removal of tumor tissue, which in turn is directly correlated with the ability to visualize microscopic lesions.…”
Section: Discussionmentioning
confidence: 99%
“…Peritoneal carcinomatosis (PC) is characterized by the progressive invasion of the peritoneal cavity by tumors of various origins, such as ovarian, colorectal, gastric, and, less frequently, non-digestive cancers 21. Metastatic CRC leads to a PC in about 30% of cases, considering both synchronous and metachronous diseases 22 and is often associated with poor prognosis 23. The therapeutic regimen for PC consists of surgery that can be associated with chemotherapy administrated either systemically or intraperitoneally 23.…”
Section: Introductionmentioning
confidence: 99%
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“…"Cytoreductive Surgery" (CRS), was first described by John Spratt in 1980 for pseudomyxoma peritonei [44] and later by Paul Sugarbaker in 1995 for peritoneal metastases [45]. CRS denotes a surgical procedure to remove macroscopically visible peritoneal metastases through a combination of peritonectomy and organ resections [45], often followed by intraoperative peritoneal chemotherapy (see section 7.2.3) and systemic treatment (see section 7.2.1) [46]. In the years since its first description, there has been debate about the value of CRS for patients with pmCRC, and the selection of patients who may benefit.…”
Section: Surgical Treatmentmentioning
confidence: 99%
“…A very specific group of oncological patients includes those suffering from peritoneal carcinomatosis (PC), in which mainly the different types of intraperitoneal forms of chemotherapy implementation to achieve a higher drug concentration in the peritoneal cavity are used [15]. One such treatment technique in recent years, proposed by the scientific team of Prof. Reymond, is the innovative pressurized intraperitoneal aerosol chemotherapy (PIPAC) [16].…”
Section: Introductionmentioning
confidence: 99%