Regenerative Endodontics-Reviving the Pulp the Natural Way: A Case Report

Abstract

Regenerative endodontic therapy (RET) offers a novel treatment option for developing teeth with pulp necrosis. In the current instance, RET was used to treat an immature mandibular permanent first molar that had been identified with irreversible pulpitis. The root canals were treated with triple antibiotic paste (TAP) and 1.5% sodium hypochlorite (NaOCl) irrigation. TAP was removed, and 17% ethylenediaminetetraacetic acid (EDTA) was used to treat the root canals during the second visit. As a scaffold, Platelet-rich fibrin (PRF) was applied. Mineral trioxide aggregate (MTA) was applied over PRF, and composite resin was used to repair the teeth. Radiographs taken from the posterior were utilized to assess the healing. The teeth displayed no signs of pain and healing after the six-month follow-up periods, and pulp sensibility tests using a cold and electric pulp tester produced no results. Conservative treatment options should be considered to save immature permanent teeth and assist in the regeneration of the root apex.

Impact of Orthodontic Treatment on Regenerative Endodontics in Immature Teeth: A Long-Term Case Study

“…These cells, when stimulated by growth factors such as proteins from dentinal root walls and surrounding matrices, are poised to migrate into the root canal, fostering proliferation and differentiation [4]. Moreover, scaffolding agents like blood clots or fibrin amplify stem cell growth [5]. Yet, in scenarios characterized by protracted bacterial intrusion in immature teeth, as depicted in our case, the vitality of residual stem cells in the apical papilla and Hertwig's epithelial root sheath (HERS) could be jeopardized.…”