Regenerative and innovative joint medication in the horse – Part 2: Efficacy and adverse effects of joint medication in the horse - A review of the literature - The pathogenesis of osteoarthritis in the horse
“…Several novel treatments based on biological processes rather than providing mere pain control have recently been introduced, but the demonstration of efficacy has been difficult (Broeckx et al 2019). The use of the interleukin-1 receptor antagonist protein (IRAP ® ), cell-based procedures such as platelet-rich plasma (PRP) and the transplantation of mesenchymal stem-cells have not proven useful for the treatment of degenerative joint disease in horses (Bertone et al 2014, Ehrle et al 2013, Fahie et al 2013, Franklin and Cook 2013. In the daily use, they are often viewed critically (Hildner et al 2011).…”
“…Several novel treatments based on biological processes rather than providing mere pain control have recently been introduced, but the demonstration of efficacy has been difficult (Broeckx et al 2019). The use of the interleukin-1 receptor antagonist protein (IRAP ® ), cell-based procedures such as platelet-rich plasma (PRP) and the transplantation of mesenchymal stem-cells have not proven useful for the treatment of degenerative joint disease in horses (Bertone et al 2014, Ehrle et al 2013, Fahie et al 2013, Franklin and Cook 2013. In the daily use, they are often viewed critically (Hildner et al 2011).…”
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