Regarding: Risk of fractures and postfracture mortality in 3980 people with primary biliary cholangitis

Authors reply: Risk of fractures and postfracture mortality in 3980 people with primary biliary cholangitis

“…Authors reply: Risk of fractures and postfracture mortality in 3980 people with primary biliary cholangitis Dear Editor, We would like to thank Prof. Chang and Prof. Gau for their interest [1] in our analysis on the incidence of fractures and postfracture death in patients with PBC in the Swedish population [2]. Despite all research efforts, the disease burden emanating from PBC remains high, and the pathophysiology is not completely understood.…”

“…Although confounders always exist in retrospective database research [4], the strengths of this study help to address important research questions based on real‐world evidence. The overall assessment of our initial observations [1] was not altered. By contrast, the additional analyses underline the high burden of disease emanating from PBC, and disease‐modifying first‐ and second‐line treatments are urgently awaited [5].…”