2019
DOI: 10.1002/lary.27813
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Regarding Laryngeal precursor lesions: Interrater and intrarater reliability of histopathological assessment

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Cited by 8 publications
(7 citation statements)
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“…The patients’ data were pseudonymized. Based on the WHO classification [ 19 ], histological diagnoses were used to label images as belonging to a benign or a malignant class. Table 1 shows the histopathologies with the number of patients and images used for the generation of the dataset.…”
Section: Methodsmentioning
confidence: 99%
“…The patients’ data were pseudonymized. Based on the WHO classification [ 19 ], histological diagnoses were used to label images as belonging to a benign or a malignant class. Table 1 shows the histopathologies with the number of patients and images used for the generation of the dataset.…”
Section: Methodsmentioning
confidence: 99%
“…Three otolaryngology specialists (experienced observers) and three otolaryngology residents (less-experienced observers), blinded to the histologic diagnoses and macroscopic image of every lesion, independently evaluated each of the 68 series of NBI-CE images, aiming to detect PVC. In cases where the observer detected at least one PVC in one or more of the images available, the lesion was characterized as PVC-positive and therefore suspect for malignancy, dysplasia, or papilloma (Figure 1a In all other cases, the lesions were declared PVC-negative (Figure 2a For the statistical assessment of the results, the histological diagnoses were grouped into four categories: 1. squamous cell carcinoma (SCC), 2. dysplasia (including mild dysplasia to carcinoma in For the statistical assessment of the results, the histological diagnoses were grouped into four categories: 1. squamous cell carcinoma (SCC), 2. dysplasia (including mild dysplasia to carcinoma in For the statistical assessment of the results, the histological diagnoses were grouped into four categories: 1. squamous cell carcinoma (SCC), 2. dysplasia (including mild dysplasia to carcinoma in situ according to the WHO classification of 2005 or low to high-grade dysplasia according to the WHO classification of 2017 [13]), 3. papillomatosis, and 4. other benign lesions.…”
Section: Methodsmentioning
confidence: 99%
“…Zur Ermittlung der diagnostischen Güte jeder endoskopischen Modalität wurde in dieser Studie der Trennpunkt zwischen positiven und negativen Befunden anhand der prognostischen Unterschiede zwischen Low- und High-Grade-Dysplasien gesetzt. Diese weisen einen signifikant unterschiedlichen Progress zu invasiven Neoplasien auf (1,6 respektive 12,5 %) [ 12 ]. Die prognostische Relevanz dieser Unterscheidung unterstützt daher dieses Design.…”
Section: Diskussionunclassified