Regarding American College of Surgeons Commission on Cancer Non-Small Cell Lung Cancer Quality of Care Measure 10RLN

Handy, John R.; Costas, Kimberly; Nisco, Steven J.; Schaerf, Raymond; Vallières, Eric; Hussain, Sanaa; Konieczny, Kasia; Weerasinghe, Roshanthi; Betzer, Cathy; Lothrop, Katherine

doi:10.1016/j.athoracsur.2016.06.020

Cited by 10 publications

(7 citation statements)

References 12 publications

(11 reference statements)

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“…The National Comprehensive Cancer Network (NCCN) indicated a minimum of 3 or more mediastinal nodal stations require examinations which can benefited patients treated by sublobar resection most ( 9 ). The American College of Surgeons Commission on Cancer (ACSCC) supported that the number of lymph nodes (LNs) examined was 10 total lymph nodes that achieve maximum benefit regardless of station for patients ( 10 ). Currently, the Union for International Cancer Control (UICC)/American Joint Committee on Cancer (AJCC) eighth edition recommends that 6 LNs is more sufficient and reliable for pathologic node staging and accurate prognostic assessment ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Exploration of the optimal number of regional lymph nodes removed for resected N0 NSCLC patients: A population-based study

Yao

Liu²,

Rao³

et al. 2022

Front. Oncol.

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BackgroundThe aim of our study was to explore the optimal number of regional lymph nodes removed (LNRs) in resected N0 non-small cell lung cancer (NSCLC) patients and identify potential risk factors.MethodsIncluded in this study were 55,024 N0 NSCLC patients between 2004 and 2015 based on the Surveillance, Epidemiology, and End Results database (SEER). All the patients were divided into No LNR group (57.8%), 1-3 LNRs group (8.1%) and ≥4 LNRs group (31.4%). Relevant clinical and patient parameters including overall survival (OS), lung cancer-specific survival (LCSS), gender, race, year of diagnosis, primary site, T stage, AJCC stage, laterality, histological type, lymphadenectomy, radiation, chemotherapy, age at diagnosis, insurance status, marital status, family income.ResultsKaplan-Meier analysis demonstrated LNRs had significantly better OS and LCSS than No LNRs in all the N0 NSCLC patients with different T stages (Logrank p<.001). Univariate and multivariate analysis showed that both OS and LCSS in ≥ 4 LNRs group were better than those in <1-3 LNRs group (OS: ≥4 LNRs group: HR, 0.583; 95%CI, 0.556-0.610; P<.001 vs.1-3 LNRs group: HR, 0.726; 95%CI, 0.687-0.769; P<.001; LCSS: ≥4 LNRs group: HR, 0.514; 95%CI, 0.480-0.550; P<.001 vs.1-3 LNRs group: HR, 0.647; 95%CI, 0.597-0.702; P<.001). In addition, whites, males, not upper lobe, large cell carcinoma and others, advance T stage or AJCC stage, no surgery, no LNR, no radiation, no chemotherapy, elder age at diagnosis, singled marital status and low family income had negative impact on prognosis of N0 NSCLC patients.ConclusionsOur study suggests that ≥ 4 LNRs can yield better survival outcomes compared with 1-3 LNRs in N0 NSCLC patients.

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Section: Introductionmentioning

confidence: 99%

Exploration of the optimal number of regional lymph nodes removed for resected N0 NSCLC patients: A population-based study

Yao

Liu²,

Rao³

et al. 2022

Front. Oncol.

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“…[27][28][29] The American College of Surgeons has endorsed removal of at least 10 lymph nodes as a quality metric in a well-intended effort to improve care. 30 Recently, Liang et al reported that a greater number of ELNs is associated with more-accurate node staging and better long-term survival of patients with stage I-IIIA resected NSCLC. 31 The study recommended 16 ELNs as the threshold for evaluating the quality of LN examination.…”

Section: Discussionmentioning

confidence: 99%

“…Lymph node sampling or dissection plays an important role in precise nodal staging by identifying lymph node involvement and determining the extent of disease and the therapeutic effect on lymph node metastatic lesion clearance 27–29 . The American College of Surgeons has endorsed removal of at least 10 lymph nodes as a quality metric in a well‐intended effort to improve care 30 . Recently, Liang et al .…”

Section: Discussionmentioning

confidence: 99%

Influence of adjuvant chemotherapy on survival for patients with stage IB and IIA non‐small cell lung cancer

et al. 2020

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Background: The role of adjuvant chemotherapy (ACT) for patients with stage IB-IIA non-small cell lung cancer (NSCLC) according to the eighth edition of the AJCC TNM staging system remains controversial. Methods: Data were collected from patients with NSCLC stage IB-IIA according to the eighth edition of the AJCC TNM staging system who underwent surgical resection from 2008 to 2015. The relationship between ACT and overall survival (OS) or disease-free survival (DFS) was analyzed using the Kaplan-Meier method and Cox proportional hazards model. Results: The study included 648 patients with completely resected NSCLC stage IB-IIA; 312 underwent ACT after surgical resection and 336 were placed under observation. After propensity score matching, 247 pairs of patients were matched and the five-year OS was 88.08% and 83.12% (P = 0.13) in ACT and non-ACT settings, respectively. Subgroup analyses demonstrated that ACT treatment was correlated with an improved five-year OS in patients with visceral pleural invasion (VPI) in the 3 < tumor ≤ 4 cm subgroup (93.98% and 68.93%, P < 0.01). Conclusions: ACT was not significantly associated with improved five-year OS in stage IB-IIA NSCLC patients. However, further subgroup analysis showed that patients with VPI in the 3 < tumor ≤ 4 cm (T2aN0M0, stage IB) subgroup might benefit more from ACT. Further studies are required to validate the findings and better systemic strategies need to be developed in these patients.

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“…Care pathways are developed in collaboration with other subspecialties when appropriate, including thoracic pathology for mutation analysis of curative intent resected lung cancer and intraoperative lymph node naming [17], radiation oncology for surgery versus stereotactic body radiotherapy for high-risk early-stage lung cancer, and emergency medicine and thoracic radiology for spontaneous primary pneumothorax and primary spontaneous pneumomediastinum management. For easy access and decision support, TSI standardization tools are posted on the website (www.…”

Section: Projectsmentioning

confidence: 99%

Regional Thoracic Surgery Quality Collaboration Formation: Providence Thoracic Surgery Initiative

Handy

Costas

McKenna

et al. 2018

The Annals of Thoracic Surgery

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Regarding American College of Surgeons Commission on Cancer Non-Small Cell Lung Cancer Quality of Care Measure 10RLN

Cited by 10 publications

References 12 publications

Exploration of the optimal number of regional lymph nodes removed for resected N0 NSCLC patients: A population-based study

Exploration of the optimal number of regional lymph nodes removed for resected N0 NSCLC patients: A population-based study

Influence of adjuvant chemotherapy on survival for patients with stage IB and IIA non‐small cell lung cancer

Regional Thoracic Surgery Quality Collaboration Formation: Providence Thoracic Surgery Initiative

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