Refractive Index Sensing Characteristics of Etched Double-Cladding Fiber Coated with Nanofilm

Jiajing, 程佳静 Cheng; Fufei, 庞拂飞 Pang; Shan, 朱姗 Zhu; Xiaobei, 张小贝 Zhang; Tingyun, 王廷云 Wang

doi:10.3788/cjl201845.0810003

Cited by 1 publication

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“…Then, the SiO 2 OF was cleaned with acetone, ethanol, and ultrapure water successively before immersing in 40 wt % HF to remove its cladding. The corrosion rate of HF to OF is approximately 1.8 μm/min according to the previous report; to ensure complete cladding removal, an etching time of 30 min was selected. Afterward, the as-obtained CROF was soaked in piranha solution ( V sulfuric acid : V hydrogen peroxide = 7:3) for 1 h to achieve surface hydroxylation.…”

Section: Methodsmentioning

confidence: 99%

SILAR Growth of ZnO NSs/CdS QDs on the Optical Fiber-Based Opto-Electrode with Guided In Situ Light and Its Application for the “Signal-On” Detection of Inflammatory Cytokine

Zou,

Wu,

Zhou

et al. 2024

Anal. Chem.

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In this study, a novel integrated photoelectrochemical (PEC) sensor platform was proposed, utilizing an optical fiber (OF) as the working electrode for guided in situ light. A CdS quantum dots (QDs)/ZnO nanosheets (NSs) n-n heterojunction was quickly and easily constructed on the OF surface by successive ionic layer adsorption and reaction (SILAR). Au nanoparticles (NPs)@dsDNA as a capturing probe were modified on the CdS QDs/ZnO NSs@OF (CZ@OF). Due to the energy transfer between Au NPs@dsDNA and CdS QDs, the resultant optoelectrode has a lower background near zero, enabling the "signalon" detection of biomarkers (interleukin-6 (IL-6) as a model). The OF-PEC biosensor demonstrated a wide linear range from 1 to 100 pg mL −1 with a regression coefficient (R 2 ) of 0.9958 and an impressive detection limit (LOD) of 0.19 pg mL −1 . More significantly, the proposed OF-PEC can be successfully used for the detection of IL-6 in serum samples from patients with pulmonary arterial hypertension, and it showed consistency and is more sensitive to trace concentrations compared to BD FACSCanto II flow cytometry used at the hospital. This holds significance for an early disease diagnosis. Therefore, the proposed OF-PEC not only achieves integration of the light source and sensing interface but also enables sensitive and accurate "signal-on" detection of IL-6. Furthermore, due to the flexibility and remote detection capabilities of OF, the application of OF-PEC is expected to be expanded more widely. This approach opens up possibilities for advances in PEC sensing.

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Section: Methodsmentioning

confidence: 99%