Refractive Errors in University Students in Central China: The Anyang University Students Eye Study

Wei, Shifei; Sun, Yu; Li, Shiming; Hu, Jianping; Yang, Xiaohui; Chen, Lin; Cao, Kai; Du, Jiang; Guo, Jiyuan; Li, He; Wang, Ke

doi:10.1167/iovs.18-24363

Cited by 38 publications

(34 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Myopia is a public health problem [9] with a high prevalence especially in the Far East [10]. Onset and progression of myopia has been associated with genetic and environmental factors [11,12].…”

Section: Discussionmentioning

confidence: 99%

Effect of Biomechanical Properties on Myopia: a Study of New Corneal Biomechanical Parameters

Fang¹,

Wei

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: To investigate corneal stress-strain index (SSI), a marker for material stiffness and corneal biomechanical parameters in myopic eyes.Methods: A total of 1056 myopic patients were included in this study. Corvis ST was used to measure SSI. Corneal biomechanics was evaluated using the first and second applanation time (A1-time and A2-time), maximum deflection amplitude (DefAmax), deflection area(HCDefArea)and peak distance at highest concavity (HC-time, HC-DefA, and HC-PD), integrated radius (IR) whole eye movement (WEM), stiffness parameter (SP), biomechanically corrected intraocular pressure (BIOP), and Corvis Biomechanical Index (CBI). Scheimpflug tomography was used to obtain mean keratometery (Km) and central corneal thickness (CCT). All participants were divided into two groups according spherical equivalent (SE) (low myopia: SE≤3.00D and high myopia: SE ≥ 6.00D).Results: The mean SSI value was 0.854±0.004. The SSI has positive correlation with A1-time((r=0.272), HC-time (r=0.218), WEM(r=0.288),SP(r=0.316)，CBI(r=0.199)，CCT (r=0.125), BIOP(r=0.230)and SE (r=0.313)(all p values＜0.01) . The SSI had a negative correlation with HCDefA (r=-0.721), HCDefArea (r=-0.665),HC-PD(r=-0.597),IR (r=-0.555), DefAmax (r=-0.564)and Km (r=-0.103) (all p values＜0.01).There were significant differences in SSI (t=8.960, p＜0.01) and IR(t=-3.509, p＜0.01)between low myopia group and high myopia group.Conclusions: In different grades of myopia, the SSI values were lower in eyes with higher spherical equivalent. It indicates that the mechanical strength of the cornea may compromise in high myopia. The SSI was positively correlated with the spherical equivalent and It may provide a new way to study the mechanism of myopia.

show abstract

Section: Discussionmentioning

confidence: 99%

Effect of Biomechanical Properties on Myopia: a Study of New Corneal Biomechanical Parameters

Fang¹,

Wei

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…In central China, the prevalence rate of myopia was 3.9% in grade 1 children and 67.3% in grade 7 children [2]. A higher prevalence of 83.2% for myopia and 11.1% for high myopia was found in central Chinese university students [3].…”

Section: Introductionmentioning

confidence: 86%

“…The Anyang University Students Eye Study (AUSES) is a university-based, cross-sectional study in which comprehensive ophthalmologic examinations were performed among university students in Anyang, Henan Province, located in central China. The detailed sample selection and methodology have been described previously [3]. Briefly, participants were selected from both the two public universities in Anyang, using random cluster sampling based on grade level.…”

Section: Participantsmentioning

confidence: 99%

Effect of Stature on Refraction and Ocular Biometry in Chinese Young Adults: The Anyang University Students Eye Study

Wang

Wei

Sun

et al. 2019

Preprint

Self Cite

View full text Add to dashboard Cite

Background There are few studies reporting the association between stature and ocular biometry as well as cycloplegic refraction in young adults. Our study determined the relationship between stature and ocular biometry as well as cycloplegic refraction in Chinese young adults. Methods This was a school-based study including university students in Anyang, Henan Province, China. Cycloplegic refraction and corneal curvature (CR) were measured using an autorefractor. Ocular biometric parameters, including axial length (AL), anterior chamber depth (ACD), and lens thickness (LT), were measured using a Lenstar LS900. Height and weight were acquired from an annual standardized physical examination, and body mass index (BMI) was calculated from these measurements. Results A total of 5657 (71.0%) subjects were available for analysis. After adjusting for age, gender, parental myopia, time outdoors, near work and weight, a 1 cm taller person could be expected to have more negative refraction as -0.023D, a 0.032 mm increase in AL, a 0.003 mm increase in ACD, a 0.008 mm increase in CR, and a 0.001 increase in axial length-corneal radius (AL/CR) ratio. With regard to weight, a 1 kg heavier person was more likely to have less negative refraction as 0.011 D, deeper ACD by 0.001mm and flatter cornea by 0.002mm. A similar pattern of significant associations was also found in BMI. Conclusions Compared to those of less height, young adults of greater height tended to have longer eyes, deeper anterior chambers, flatter corneas, higher AL/CR ratio, and more negative refraction after controlling for potential confounders. In contrast, heavier and higher BMI persons were more hyperopic. The differences in stature may partially explain the variation in refraction and ocular biometric parameters.

show abstract

“…Research in Singapore revealed that the prevalence of myopia is 62.0% in children age 7 to 9 years 5 and in Guangzhou, China, the prevalence is 49.7%. 6 Among university students in central China, the myopia prevalence is 83.2%, 7 and it is 96.5% in 19-year-old men in Seoul, Korea. 8 The reported prevalence of myopia is 11.9% in Australia, 9 20.0% in the United States, 10 21.1% in urban India, 11 and 16.5% in Nepal.…”

Section: Introductionmentioning

confidence: 99%

Protective effects of increased outdoor time against myopia: a review

Zhang

Deng

2019

J Int Med Res

View full text Add to dashboard Cite

Myopia has become a major cause for concern globally, particularly in East Asian countries. The increasing prevalence of myopia has been associated with a high socioeconomic burden owing to severe ocular complications that may occur with progressive myopia. There is an urgent need to identify effective and safe measures to address the growing number of people with myopia in the general population. Among the numerous strategies implemented to slow the progression of myopia, longer time spent outdoors has come to be recognized as a protective factor against this disorder. Although our understanding of the protective effects of outdoor time has increased in the past decade, considerably more research is needed to understand the mechanisms of action. Here, we summarize the main potential factors associated with the protective effects against myopia of increased outdoor time, namely, exposure to elevated levels and shorter wavelengths of light, and increased dopamine and vitamin D levels. In this review, we aimed to identify safe and effective therapeutic interventions to prevent myopia-related complications and vision loss.

show abstract

Refractive Errors in University Students in Central China: The Anyang University Students Eye Study

Cited by 38 publications

References 56 publications

Effect of Biomechanical Properties on Myopia: a Study of New Corneal Biomechanical Parameters

Effect of Biomechanical Properties on Myopia: a Study of New Corneal Biomechanical Parameters

Effect of Stature on Refraction and Ocular Biometry in Chinese Young Adults: The Anyang University Students Eye Study

Protective effects of increased outdoor time against myopia: a review

Contact Info

Product

Resources

About